A Case of Periventricular Leukomalacia and Necrotizing Enterocolitis in a Surviving Twin after Intrauterine Fetal Death in Twin Pregnancy / 대한주산의학회잡지

Single fetal death in the late second or the third trimester in twin pregnancy is associated with high mortality and morbidity of surviving co-twin. Monochorionic twins have an increased risk of intrauterine fetal death, its prognosis is poor, and assoiated with neurological damage in the surviving co-twin. And renal, cutaneous, pulmonary, gastrointestinal complications are also reported. Especially, survivals with twin-to-twin transfusion are at risk for development of renal insufficiency, periventricular leukomalaca, and necrotizing enterocolitis. In this report, we present a case of surviving co-twin complicated with periventricular leukomalacia and necrotizing enterocolitis delivered after intrauterine single death in twin pregnancy.

A Case of Swyer Syndrome Diagnosed in Infant / 대한주산의학회잡지

Swyer syndrome is characterized by a female phenotype, normal to tall stature, sexual infantilism with primary amenorrhea and 46,XY karyotype. The internal genitalia are female with uterus and full vagina, but have no ovaries or testis. Swyer syndrome is often diagnosed when young adults are evaluated for delayed puberty, as menstruation dose not occur naturally. We experienced a case of Swyer syndrome diagnosed incidentally in course of evaluating intrauterine growth retardation and delayed growth in infant. So, we report a case of Swyer syndrome with a brief review of literatures.

The Study of Hypoglycemia in Fullterm with Large for Gestational Age Newborns

PURPOSE: This study is to determine the frequency, onset age, and the proper duration of evaluation in fullterm large for gestational age (LGA) newborn infant. We also compared risk factors between hypoglycemic and euglycemic newborns. METHODS: 77 term newborns from non-diabetic mothers who were greater than 90 percentile on Lubchencho growth curves were included in this study. Blood glucose levels were checked at age 1, 2, 3, 6, 12, 24, 36, 72, 96 hours and cord blood with rapid strip test. Hypoglycemia was defined as a serum glucose less than 35 mg/dL at less than 3 hours, less than 40 mg/dL between 3 to 24 hours, and less than 45 mg/dL at greater than 24 hours of age. RESULTS: In 77 fullterm neonates with LGA (4,185+/-224 g, 39+/-0.9 wk), frequency of hypoglycemia was 9 case (11.7%) and 3 case of them (3.9%) had clinical symptoms of hypoglycemia. The mean onset age and mean serum glucose level were 2.56+/-2.13 hour and 34+/-6 mg/dL. Glucose level started to decrease in 1 hour and showed lowest at 2 hours. No hypoglycemic patients were noticed after 6 hours of life. There were no significant differences in delivery type, sex, preeclampsia and meconium staining between hypoglycemic and euglycemic newborns except maternal body weight greater than 80 kg (P<0.05). CONCLUSION: Screening of hypoglycemia after 6 hours of age in fullterm LGA newborn infants might not be necessary. And neonatal hypoglycemia should be considered if maternal body weight greater than 80 kg.