Squamous Cell Carcinoma of the Pancreas with Invasion of Duodenum and Pylorus

Squamous cell carcinoma of the pancreas is a rare variant of pancreatic ductal cell carcinoma. Its biologic behavior and clinical features are known to be similar to the much more common ductal adenocarcinoma of pancreas. A 70-year old man with postprandial vomiting symptom was admitted to our hospital. Initial endoscopy and abdominal CT showed that 6cm sized submucosal tumor on pylous or duodenum invaded the pancreas. Subtotal gastrectomy with partial pancreatic resection was done. The resection specimen revealed of metastatic squamous carcinoma of stomach and duodenum. Follow up CT was revealed that multiple liver metastasis and a large mass in peripancreatic space. The mass was confirmed invasive squamous cell carcinoma of pancreas by aspiration biopsy. The patient died of cancer cachexia 50 days after operation. We report an unusual case of squamous cell carcinoma of the pancreas which was invaded to duodenum and pylorus with a review of literature.

The Efficacy of Adding Postoperative Oral Antibiotics after Parenteral Antibiotic Therapy in Acute Appendicitis

PURPOSE: To evaluate the efficacy of the postoperative oral antibiotics in acute appendicitis. METHODS: This study compared 126 patients diagnosed with appendicitis in 2004, who did not take oral antibiotics after the postoperative treatment (group 2), with 119 patients diagnosed with appendicitis in the year of 2003, who did take oral antibiotics after the parenteral postoperative antibiotics regimen (group 1). RESULTS: The clinical, operative, and bacterial outcomes were similar. Only one infectious complication was detected in each group (group1; 1/119, group2; 1/126). CONCLUSION: This study suggests that adding a course of oral antibiotics, after completing a course of parenteral antibiotics, does not decrease The rate of postoperative infectious complications in appendicitis patients.