Needling with 5-Fluorouracil for the Treatment of Non-Functioning Functioning Filtering Blebs

The functional loss of bleb due to fibrosis after trabeculeetomy is not rare in glaucoma patients but it is possible the restore to function of bleb with simple treatment. The authors reviewed 15 eyes of 14 patients at least 6 months follow up after the needling and 5-FU injection for the non-functioning bleb after trabeculectomy, in terms of intraocular pressure control and complication. After needling of the non-functioning bleb, 5-FU was used 2mg dosage at one time and average total dosage of 12mg, subconjunctivally. The intraocular pressure was controlled under 21mmHg in 12 of 15 eyes (80%) after this procedure with or without medication. The complication observed is a corneal epithelial defect in 3 of 15 eyes (20%). Therefore, the needling and 5-FU injection for non-functioning bleb after trabeculectomy is recommended before reoperation because it is simple and safe method.

Size of Capillary Nonperfusion and their Prognosis in Branch Retinal Vein Occlusion Patients

Sudden loss of visual acuity and visual field can occur in the vast majority of BRVO patients. One third to half of the patients recover from impared cision even without specific treatment, but it is unlikely when complication such as macula edema, capillary nonperfision, neovascularization and vitreous hemorrhage are accompanied. The authors reviewed 55 patients with branch retinal vein occlusion(55 eyes) in regard of the size of capillary non perfusion, and divided them into two groups; the perfused group(15 eyes) in which the area of capillary non perfusion is less than 5 disc diameter, and the nonperfused group(40 eyes) in which the area is more than 5 disc diameter. The freqnency of the development of neovascularization and vitreous hemorrhage, and the final visual outcome between two groups were compared. Neovascularization occurred in 3 eyes of perfused group and 23 eyes of nonperfused group, and vitreous hemorrhage occured in 4 eyes of nonperfused group, and vitreous hemorrhage occurred in 4 eyes of nonperfused group. There was no statistic al difference between two groups in the final visual acuity.