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Indian J Biochem Biophys ; 2006 Oct; 43(5): 323-6
Artículo en Inglés | IMSEAR | ID: sea-26815

RESUMEN

The extraction and carrier-facilitated transport of amino acids (leucine, valine and glycine) was studied through chloroform bulk liquid membrane system using a series of non-cyclic receptors such as diethylene glycol (1), diethylene glycol dimethyl ether (2), diethylene glycol dibutyl ether (3), diethylene glycol dibenzoate (4), triethylene glycol (5) and tetraethylene glycol (6). The amount of amino acid extracted and transported depends mainly upon the structure and the concentration of the receptors and also on the concentration of amino acid. The receptors 1 to 4, having small chain length and flexible end groups, formed stable complexes with amino acids, and the flexibility of receptors in different conformational forms was responsible for their carrier ability, while the receptors 5 and 6, having larger chain length showed poor carrier ability. Hydrophobicity of amino acids also play an important role in the extraction as well as transport process.


Asunto(s)
Aminoácidos/química , Transporte Biológico , Transporte Biológico Activo , Proteínas Portadoras/química , Portador Sano , Membrana Celular/metabolismo , Glicina/química , Leucina/química , Modelos Biológicos , Modelos Químicos , Factores de Tiempo , Valina/química
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