RESUMEN
OBJECTIVE@#To observe the changes of cardiac functional indicators in spontaneously hypertension rats (SHR) suffered by struck injuries of soft tissues, form which to discuss the significance in relationship between injury and disease.@*METHODS@#SHRs were divided into four groups according to the degree, and whose thigh was struck with the homemade hit instrument. Then the blood pressure, heart rate as well as serum biochemical indicators (CK, CK-Mb, LDH, Cr, BUN, HBDH and AST) were examined. In addition, the morphological changes of heart, brain and kidney were also observed.@*RESULTS@#The observe values of heart rate and blood pressure of SHRs seemed have relation to the degree of damage, but there were no statistically significance between different hit degree groups. In terms of serum biochemical indicators, all seven indicators of the hit group had significant difference with that of the control group, and the AST CK, CK-MB levels were difference between the group of different strike degree.@*CONCLUSIONS@#Struck injuries of soft tissues can result in forepart damage of cardiac muscle. The biochemical indicators reflect the degree of injury, and they could be used as a type of objective enzymology indicators for analysis of the relationship between injury and disease in forensic practice.
Asunto(s)
Animales , Femenino , Masculino , Ratas , Aspartato Aminotransferasas/sangre , Biomarcadores/sangre , Presión Sanguínea , Creatina Quinasa/sangre , Corazón/fisiopatología , Frecuencia Cardíaca , Miembro Posterior/lesiones , Hipertensión/fisiopatología , Riñón/fisiopatología , Miocardio/patología , Distribución AleatoriaRESUMEN
<p><b>OBJECTIVE</b>To investigate the polymorphisms of 15 STR loci of Han population in Yan'an.</p><p><b>METHODS</b>Blood samples were obtained from 100 unrelated Han individuals in Yan'an. DNA templates were screened by AmpF/STR Identifiler kit and ABI3100Avant DNA analyzer.</p><p><b>RESULTS</b>The allele frequencies of 15 STR loci ranged from 0.005 to 0.550, and the genotype frequencies ranged from 0.010 to 0.310. The combined match probability was 2.5x10(-17) and combined EPP was 0.999999999.</p><p><b>CONCLUSIONS</b>The 15 STR loci used in this study were highly polymorphic in Han population in Yan'an and suitable for population study and forensic cases in this region.</p>