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LJM-Libyan Journal of Medicine. 2009; 4 (3): 104-106
en Inglés | IMEMR | ID: emr-146589

RESUMEN

Clindamycin has been used successfully to treat pneumonia and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. However, inducible clindamycin resistance has been described as a cause of treatment failure of such infections. A total of 159 staphylococcal isolates from different clinical specimens from burn patients in Tripoli Burn Center were tested for inducible clindamycin resistance by the disk-diffusion induction test. Inducible clindamycin resistance was detected in 66.2% of 65 methicillin-resistant S. aureus isolates and in none of 55 methicillin-sensitive S. aureus, 10 methicillin-resistant coagulase negative staphylococci and 29 methicllin-sensitive coagulase negative staphylococci isolates. In our setting, clindamycin can be used for the treatment of infections due to staphylococci, but we recommend that staphylococci isolates, particularly methicillin-resistant S. aureus, are tested by the D-test before treatment


Asunto(s)
Clindamicina/farmacología , Farmacorresistencia Bacteriana , Infecciones Estafilocócicas/tratamiento farmacológico , Staphylococcus/efectos de los fármacos , Staphylococcus aureus/aislamiento & purificación , Pruebas de Sensibilidad Microbiana , Quemaduras/microbiología , /farmacología , Infección Hospitalaria
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