neuroleptic malignant syndrome

The neurolptic malignant syndrome is a rare serious idiosyncratic reaction to neuroleptic drugs. It is characterized by muscular rigidity, fever, altered consciousness, autonomic dysfunction, elevated level of creatine kinas, and leukocytosis. It has a universal occurrence, but has not been reported from the Arab countries to the best of our knowledge. We describe three cases from Saudi Arabia and review the literature for possible risk factors in this potentially fatal condition