Alkaloids from erythrina corallodendron linn and their pharmacological activities

During a careful search for bioactive alkaloidal constituents from the alcoholic extract of Erythrina corallodendron Linn leaves, three alkaloids namely, erysodine [1], erythirinine [2] and 8-oxoerythrinine [3] were isolated. These compounds are reported here for the first time from such species. Structures of the isolated compounds [1-3] were assigned by intensive studies of their NMR and MS spectral data and comparison with related structures. The pharmacological activities of the isolated alkaloids are presented

new triterpenoid from glycyrrhiza glabra L. and antimicrobial activity

A new pentacyclic triterpenoid was isolated from the minor constituents of local liquorice roots. The structure was determined by means of [1]H-H COSY, [13]C APT, HMQC, HMBC experiments and MS spectroscopy. Another triterpenoid was isolated in a very small amount and its structure was assumed from [1]H-NMR and MS only. The antimicrobial activity of the pentacyclic triterpenoids against Staphylococcus aureus; Escherichia coli, and Candida albicans were investigated. Compound 1 had the highest antibacterial activity against Escherichia coli: and Staphylococcus aureus, while compound 2 had the highest antifungal activity against Candida albicans