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1.
Artículo en Inglés | IMSEAR | ID: sea-152044

RESUMEN

Background and objectives: Stature of an individual is an important parameter of personal identification. In this study stature was estimated from the percutaneous measurement of length of Tibia in living. Methodology:400 students (200 male and 200female) in age group of 18-21 years were studied. Heights of the subject in standing position, percutaneous length of Tibia were measured on both sides. Regression formulae and Multiplication factors were derived for both sexes for right and left Tibia for estimation of stature Results: In both sexes stature estimated by regression formulae for percutaneous length of tibia was similar to average measured stature with an error of less than 1 cm. In both sexes stature estimated by derived multiplication factor for length of tibia was similar to average measured stature with an error of less than 1cm. There was no significant difference in the percutaneous measurement of length of right and left tibia in both sexes, thus showing bilateral symmetry in the length of Tibia in both sexes. Interpretation and Conclusion: This study will be of help to the forensic experts when whole leg only is available for forensic investigation for estimation of stature and in anthropological studies. Regression formulae are more dependable than multiplication factor for estimation of stature.

2.
Indian J Physiol Pharmacol ; 2007 Apr-Jun; 51(2): 195-8
Artículo en Inglés | IMSEAR | ID: sea-107574

RESUMEN

Infertility is on the rise in today's world. A subnormal sperm count is frequently encountered in infertile couples. Clomiphene citrate, 1-[p-(beta-diethyl aminoethoxy) phenyl]-1,2-diphenyl chloroethylene, is an orally active nonsteroidal agent distantly related to diethylstilbestrol. It is thought to stimulate pituitary gonadotropin release by excluding estradiol from hypothalamic receptor sites. This interaction neutralizes the normal negative feedback control of estrogen and results in enhanced secretion of LH-RH, FSH-RH and gonadotropins. Testosterone is produced by the Leydig cells in response to LH secretion. The concentration of testosterone in the tubular environment is believed to maintain the gametogenic function of the testis. Clomiphene citrate in the dose of 25 mg daily for 25 days with five days rest was administered to 25 extreme oligozoospermic men (group I) and 40 moderate oligozoospermic men (group II) the cycle being continued for three months). Repeat semen analysis was done at the end of three months and all the routine seminal parameters were reevaluated. The data thus obtained was analyzed using Student's paired 't' test. The mean sperm count in Group I increased from 3.84 +/- 0.32 to 8.2 +/- 1.58 (P < 0.05) and in Group II from 13.05 +/- 0.48 to 24.55 +/- 1.73 (P < 0.001). The mean motile sperm count in Group I increased from 1.74 +/- 0.25 to 3.92 +/- 0.83 (P < 0.05) and in Group II from 8.27 +/- 0.40 to 10.05 +/- 0.56 (P < 0.01). Thus clomiphene citrate exerts its effect on spermatogenesis by raising the endogenous serum FSH, LH and testosterone levels to initiate and maintain gametogenesis (10). Researchers opined that this increase in endogenous gonadotrophins manifests itself in improving the sperm count, sperm motility and to certain extent morphology of the sperms, when there is no end-organ pathology.


Asunto(s)
Clomifeno/administración & dosificación , Fármacos para la Fertilidad Masculina/administración & dosificación , Humanos , Infertilidad Masculina/tratamiento farmacológico , Células Intersticiales del Testículo/metabolismo , Masculino , Oligospermia/tratamiento farmacológico , Recuento de Espermatozoides , Motilidad Espermática/efectos de los fármacos , Testosterona/análisis , Resultado del Tratamiento
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