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Al-Azhar Medical Journal. 2007; 36 (2): 249-256
en Inglés | IMEMR | ID: emr-145846

RESUMEN

Reactive oxygen species [ROS] have been implicated in the pathophysiology of many diseases such as atherosclerosis, Alzheimer's and Parkinson's diseases. Additional evidence also suggests ROS may play a role in the decline in neuronal function during normal aging. Phytochemical investigation of koelreuteria elegans resulted in isolation of a new benzoic acid monoglycoside, its structure was established as: benzoic acid 4-0-alpha-L-arabinopyranoside [compound 1] which exhibited strong radical scavenging properties on lipid peroxidation, hydroxyl radical and superoxide anion generation. Three other known flavonol glycosides; quercetin-3-O-alpha-L-arabinopyranside [compound 2], kaempferol-3-O-alpha-L-arabinopyranoside [compound 3] and ombuin 3-O-alpha-L-rharnnopyranosyl-6-D-glucopyranosyl [compound 4], in addition to a triterpene saponin 3-O-beta-D-glucopyranosyl[1-2][alpha-L-rhamnopyranosyl[1-3]] beta-D-glucuronopyranosyl 28-0-angeloyl-camelliagenin A [comped 5] were also isolated


Asunto(s)
Antioxidantes , Glicósidos , Quercetina , Extractos Vegetales/aislamiento & purificación
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