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Aims : The aims are to study the spectrum of non-neoplastic and neoplastic lesions of lung and to study the incidence of lung cancers with reference to age, gender, lifestyle and occupation. Materials and Methods: The study is done over a period of 2 years (May 2009 to April 2011) in the Department of Pathology, GGH,Guntur. Total of 52 lobectomy specimens were studied. Formalin fixed, paraffin embedded H & E stained tissue sections were studied. Special stains (Gomorri’s methenamine silver stain and Periodic acid schiff) were done whenever necessary. Immunohistochemistry was done in diagnostically difficult cases. Results: Neoplasms constituted 38.4% of total lesions.Majority of lung tumors occurred in the fifth and sixth decade. M:F sex ratio is 4:1. On chest x-ray/CT scan chest, majority of lung tumors presented as mass lesion. Right side of the lung is more commonly affected than the left.Cigarette smoking is the major etiological factor in the causation of lung carcinoma. Among the primary tumors, adenocarcinoma constituted largest group followed by squamous cell carcinoma. Conclusion: from the present study it is concluded that adenocarcinoma is now the most common lung carcinoma in all race and sex groups.There is a strong association between lung cancer and smoking.Chest radiograph and CT scan aid in the diagnosis and anatomical localisation of lung tumor.
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Epithelioid Trophoblastic Tumor (ETT) is a rare neoplasm of the chorionic type intermediate trophoblastic cells. It is a neoplasm of reproductive age women and usually follows a gestational event. ETT can occur at both intra uterine and extra uterine sites and can be confused with other entities such as squamous cell carcinoma, placental site nodule, placental site trophoblastic tumor etc. Hence, proper diagnosis of this tumor is necessary to avoid unnecessary, excessive treatment as surgical treatment is considered sufficient for ETT. We present a case of ETT in a 36 year old female, who came with symptoms of pain abdomen, white discharge per vaginum and a cervical mass.
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Multiple system atrophy (MSA) is a sporadic, progressive neurodegenerative disorder of unknown etiology, characterized by various combinations of autonomic, cerebellar, pyramidal and extra pyramidal signs. Based on the consensus criteria, patients with MSA are classified as MSA-c and MSA-P. MRI plays an important role in the early diagnosis. The characteristic finding hot "cross bun’’ sign is seen in MSA of cerebellar type Here we present a case of MSA-C in 52 years old male patient.
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Blue nevi can present clinically as blue, gray, brown, or black solitary nodules or plaques on the skin. Histologically, they represent collections of melanocytes and melanophages in the dermis. We presented here a case of a cellular blue nevus in a 20 years old man that presented as an enlarging blue-gray nodule on the right buttock. These cases can be challenging both clinically and histologically because malignant melanoma or malignant transformation of a blue nevus could be considered.
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Schwannomas are truly encapsulated neoplasms of the human body and are always solitary. Only 1-2% occur intraorally with tongue being the most common site. A 20yr old male presented with a painless, slow growing swelling on the left side of the tongue for the past 1 year. Fine needle aspiration cytology was done and a benign mesenchymal lesion, possibility of Schwannoma was given. Biopsy of the tumour was performed and sent for histopathological examination which confirmed the diagnosis of Schwannoma.