RESUMEN
Plant mediated green synthesis of silver nanoparticles (AgNPs) holds promising applications in the field of Biomedicine, Food packaging and Wound healing. In the present investigation, biofabrication of AgNPs was performed using the aqueous extracts of Campsis sp. (Family Bignoniaceae) leaves and flowers growing in the premises of Kirori Mal College, University of Delhi, Delhi. Optimization of AgNPs was performed to analyse the varying effect of pH (6.0, 8.0, 10.0) and silver salt concentration (2mM, 4Mm and 6Mm) in controlling the shape and size of AgNPs which in turn governs their further applications. Interestingly, change in colour of the reaction mixture from pale yellow to reddish brown indicated the formation of AgNPs. These AgNPs were further characterized by UV-Visible spectroscopy and showed peak in the range of 400-450 nm which confirmed the synthesis of silver nanoparticles. Dynamic light scattering and zeta potential analysis (DLS-Zeta) confirmed the size of AgNPs around 200-300 nm. A significant zone of inhibition was observed for both Staphylococcus aureus (gram-positive) and Escherichia coli (gram-negative) bacterial strains which revealed the antimicrobial potential of Campsis sp. AgNPs. Therefore, Campsis AgNPs may provide a green, eco-sustainable alternate method for sustainable production of nanomaterials for biomedical applications. These AgNPs may also show tremendous applications in food packaging, wound healing and biomedical fields.
RESUMEN
The rapid growing industry of global economic importance is exploring the novel material synthesized at the nanoscale. Engineered nanoparticles (ENPs) have been manufactured with specific shape, size, surface properties and unique functionalities such as catalytic behaviour, increased strength, improved thermal and electrical conductivity. These advancements have opened the door to new applications in biomedicine, nanoenergetic materials and functional nanocomposites including cancer therapy, drug delivery, tissue engineering, regenerative medicine, biomolecule detection, and antimicrobial activities. In cancer therapies, nanoparticulate delivery systems allow ENPs greater penetration of therapeutic and diagnostic substances within the body while posing fewer risks than conventional cancer therapies. Evidences suggested that ENPs offer some substantial danger to the environment by its toxicological effects when they are exposed to the environment, which leads to the chronic issues of nanopollution. The aquatic environment is at the greatest risk from ENPs, as it serves as a sink for nearly all environmental contaminants. Despite these challenges, ENPs holds promise to in different field as well as minimize environmental pollution, by employing the innovative environmental remediation methods. There are gaps in understanding the fate of ENPs in the environment hence more stringent and critical research is the need of the hour. It also call for the advancement of tools and techniques that can accurately quantify and analyze the uptake of ENPs into biological systems.This review includes the different types of ENPs their sources and physiochemical characteristics and the ultimate fate of these ENPs in the environment.
RESUMEN
Agriculture and society are intertwined. Agriculture is necessary for human survival and social sustainability in India. Eco-friendly agriculture practices nurture ecosystems to solve current societal issues. Indian ecosystems are marred by pollution, imbalance, climate changes, food crisis, various diseases, and mal-nourishment continue as a major concern. The traditional environmental remedial strategies appear relatively ineffective in the ever expanding use of pollutants that pervade the water, air and soil environment. Nanotechnology provides an efficient, environmentally friendly and cost-effective solutions to the global sustainability challenges that society is facing. Nanotechnology utilizes nanomaterials that have remarkable physical and chemical features to make smart functional materials for developing sustainable technologies. Nanotechnology seems to be very promising in sustainable environment development, sustainable agriculture, renewable and economically energy alternative through use of nanomaterials for detection, prevention, and removing pollutants. The development of nanotechnology in India has huge potential to address the challenges like providing drinking water, healthcare, nano-based industry and sustainable agriculture. This review highlights the recent nanotechnology applications to meet the global challenges in providing clean energy technology, water purification, and greenhouse gases management. In addition, effort has been made to analyse the opportunities and limitations in engineered nanomaterials safety, solid waste management, reducing pollution of air water and soil.
RESUMEN
Gladiolus spikes with fully turgid petals need to have a longer shelf life to fetch a higher price as well as display value. To improve the life duration of ornamental flowers, the ability of plants to produce silver nanoparticles (AgNP) was exploited. The ability of plants to produce AgNP when treated with silver nitrate solutions was juxtaposed by using Gladiolus (cut flowers): (i) To find the appropriate concentration of AgNO3 suitable for increasing shelf-life of Gladiolus cut flowers; (ii) To prepare silver nanoparticle from AgNO3; and (iii) To confirm the formation of silver nanoparticle using UV-vis spectrophotometry. Two different reductants (dehydrogenases present at the surface of the plant cells and sucrose) demonstrated the reduction of Ag+ to generate AgNPs. DLS (Dynamic Light Scattering) study revealed the presence of NPs in the AgNO3 salt solution incubated with Gladiolus cut flowers. The DLS data also suggested that the size of AgNPs decreased with increasing concentration of AgNO3. In the present study, along with silver nitrate, sucrose was also used. The shelf life and display value of the cut Gladiolus can be increased and optimized by incubating it in sucrose solution in combination with AgNO3.
RESUMEN
Research in the field of nanotechnology has witnessed rapid increase in the synthesis of Engineered nanoparticles (ENPs). This has even led to development of new discipline of Nanotoxicology. Advances in the field of Nanotoxicology further led to development of new domain-nanoinformatics. This new domain of nanoinformatics provides a computational perspective to biology and nanotechnology addressing multi level integration. Nanoinformatics not only helps in predicting nanoparticle structure, composition and behaviour but also covers raw data management, analysis of data derived from biomedical applications and simulation of nanoparticle interactions with biological systems. In addition, it accelerates nano-related research and applications into clinical practice. There are various computational models developed to study the key steps in nano-medicine like drug encapsulation and release, nanoparticle targeting, delivery and uptake and nanoparticle effects on cells and tissues. These prospects have opened up a large domain enabling possibilities of nanomedicine and frontiers for clinical practice and biomedical research in a cost-effective manner along with various applications including studies in clinical trials, toxicity assays, drug delivery systems. This review highlights new approaches for Engineered nanoparticles (ENP) risk assessment and regulation.