DDS- syndrome: a rare side effect of dapsone in leprosy patients

A 35-year-old male suffering from mid-borderline leprosy was put on multidrug therapy. Six weeks after the commencement of therapy he developed features of DDS- syndrome. Dapsone was immediately stopped, he was put on oral steroids. The patient gradually improved and the liver functions became normal within few weeks. The steroids were gradually tapered off. Dapsone was replaced with quinolones