RESUMEN
Background: Syphilis is a sexually transmitted disease caused by bacteria named Treponema palladium, subsp. pallidum. Nearly 1.36 million pregnant women are known to be affected by syphilis in the developing countries. When left untreated syphilis during pregnancy can result in adverse fetal outcomes such as spontaneous abortion and stillbirth. Objective of the study was to evaluate the seroprevalence of syphilis among pregnant females attending Antenatal Clinic (ANC).Methods: A hospital based cross-sectional study was done over a period of six months from January to June 2019. A total of 132 pregnant females were included in the study who attended Antenatal Clinic for routine checkup whose blood samples were sent to Microbiology Laboratory for screening for syphilis by Rapid Plasma Reagin (RPR) test.Results: Out of 132 samples of pregnant females screened for syphilis, none of the sample was found reactive for syphilis by RPR test. Maximum patients (57.6%) belonged to age group 20-25 years followed by (27.3%) of 26-30 years. 30.3% patients belonged to urban areas and 69.7% patients belonged to rural areas. Majority of patients (80.3%) belonged to first trimester, followed by (18.9%) patients to second trimester and (0.8%) patients to third trimester. 78.8% patients were from lower socio-economic class followed by 12.9% patients from middle class and 8.3% patients from upper class.Conclusions: Although zero percent syphilis prevalence was observed in this study, it is recommended that free screening for syphilis should be offered to all pregnant females visiting Antenatal Clinic.
RESUMEN
Background: We aimed to evaluate the predictive value of two screening tests - 50 gm GCT and 75 gm GTT for adverse maternal and fetal outcome in patients with gestational diabetes mellitus. Methods: This was a prospective study of 200 antenatal women booked at tertiary care hospital Delhi during the year 2010-2012. Pregnant females at 24-28 weeks gestation were randomly selected and subjected to 50 gm GCT and 75 gm GTT. The women’s history, clinical examination recorded, 50 gm GCT and 75 gm GTT values recorded and the two tests were compared for maternal and fetal outcome. Results: 75 gm GTT had higher specificity, positive and negative predictive values as compared to 50 gm GCT for both maternal and fetal outcome. However 50 gm GCT was more sensitive for predicting maternal and fetal complications. Conclusions: 75 gm GTT is better than 50 gm GCT for predicting adverse maternal and perinatal outcome in gestational diabetic patients.