survey on the drugs of animal origin used in unani medicine as possible alternative for the cure of sizable human ailments

As all of us know that science is the systematic and unbiased study of all the things around us which can be seen or detected, while at some places it has also been mentioned that 'science is an unbroken continuous process in the crucible of time in which each generation makes its contribution'. It is a part of this process that, inspired by their predecessor, new generation of scientists make advances. They always take into consideration the earlier contributions as these have been a source of inspiration for the researchers of new generation and may prove to be stepping stone for future scientific achievements

Porocarcinoma: a rare sweat gland malignancy

Eccrine Porocarcinoma [ECP] is a malignant tumour arising from the intraepithelial ductal parts of the sweat gland. It has also been described as malignant hidroacanthoma simplex, sweat gland carcinoma, malignant intra-epidermal eccrine poroma, eccrine poroepithelioma, dysplastic poroma, malignant syringo acanthoma and porocarcinoma. Treatment with wide local excision but metastatic lesions can be treated with chemotherapy. Here, we present a case report of 52 years old male who presented with a fungating growth on left pre-auricular region that came out to be a case of ECP on histopathological examination

comparative study on the inhibitory trend of triphenyltin chloride on the activity of digestive enzymes of two insects

Organotin compounds are widely used mostly as antifeedant. However, in the present investigation the inhibitory effects of one of the organotin compound [Triphenyltin Chloride] on the digestive enzymes of Hieroglyplus nigrorepletus and Leptocorisa varicornis have been studied. It was found [that .05% to 0.10% concentrations inhibited invertase and amylase enzymes of both the insects in progressive manner. The inhibition in the activity of both the enzymes was more in H. nigrorepletus than L. varicornis i.e. 55% and 61% and 44 and 46%, which suggest that this chemical may be useful for the control of pests of agricultural crops

Organotin compound as inhibitor of digestive enzymes of gastrimargus transverses and oxya velox

In the present investigation it was observed that the injection of each concentration of TPTA into the haemocoel of Gastrimargus transverses and Oxya velox caused greater inhibition in the activity of both the enzymes. The trend of inhibition in the activity of both the enzyme [amylase and invertase] was progressive from lower to higher concentration as well as related with time following injection. In G. transverses, the injection of different concentratons produced more inhibition in the activity of amylase than invertase, whereas in O. velox invertase activity was inhibited more than that of amylase. The highest inhibition was recorded by 0.1% concentration at 48 hours following injection i.e. 64%, 63% and 56 and 52% repectively for invertase and amylase in G. transverses and O. velox

Inhibitory effect of Triphenyltin acetate on the digestive enzymes of hieroglyphus nigrorepletus bol

In the present investigation the effect on the digestive enzymes [invertase and amylase] of Hieroglyphus nigrorepletus was studied following ingestion of leaves treated with different concentration of triphenyltin acetate. It was found that the inhibition in the activity of the enzyme, was progressive from lower to higher concentration of TPTA till the maximum inhibition attained by 35 ppm concentration [41% amylase and 43% invertase]. It was further observed that this decrease in the activity of both the enzymes was less as compared to the inhibition in the activity of the enzymes obtained by topical, injection methods or mixing it into mixture of enzyme prior to incubation

Distribution of free amino acids in the whole body homogenate of fully grown larvae of corcyra cephalonica and its parasite, chelonus blackburni

It was observed that during the growth of larva, there is an increase in its size as well, which requires more utilization of protein. As we know that for the synthesis of protein in the body of larva it requires more amino acids, hence there is a continuous removal of amino acids from the metabolic pool, giving faint appearance in the analysis in Corcyra cephalonica, which is similar to the observations of Ganti [1984]. Almost the same pattern of amino acids was also recorded in the whole body tissue of its parasite, Chelonus blackburni. From the present observations on C. cephalonica and C. blackburni there appears to be a little difference in the pattern of the amino acid in the larval and whole body tissue homogenate respectively. It indicates the adaptability of the parasite to host. Therefore, from the present findings, it is concluded that by developing the colonies of Chelonus blackburni and their release in the stored grains infected by Corcyra cephalonica may be useful for its control as biological control measure

Study on Pharmacokinetics of juliflorine in rabbits and chick embryonated eggs

Juliflorine, an antimicrobial and main alkaloid of Prosopis juliflora, has been studied for its pharmacokinetics and bioavailability in a single dose experiment conducted in rabbits and chick embryonated eggs. Bioactive juliflorine could not be detected in rabbit sera and also in various organs, such as heart, liver, brain, kidney, lungs and body tissues of the 12-14 days old chick embryonated eggs. On the contrary bentonite particles, coated with juliflorine, were detected mainly in heart and a few in kidney tissues of chick embryo. This shows that juliflorine has some affanity with heart tissue and little with the kidney tissue. This alkaloid probably reacts firmly with tissue and/or metabolizes quickly and looses its biological activity. On the other hand in vitro study shows that it precipitates at slightly alkaline pH or reacts with some serum component but retains some of its antibacterial activity