Leiomyosarcoma of uterus--a case report.

Leiomyosarcoma of uterus is a very rare malignant mesenchymal tumour of uterus. It may arise from the uterine myometrium de novo or may be transformed from a pre-existing benign leiomyoma. A 55-year-old female presenting with 20-22 weeks size of uterus and bleeding per vagina was clinically diagnosed as a case of leiomyoma uteri and cervical polyp, was subjected to abdominal hysterectomy. The tumour mass was later confirmed histologically as leiomyosarcoma of uterus presumed to be transformed from pre-existing leiomyoma uteri.

An autopsy case of sudden death in a patient with giant cell myocarditis.

We present a case of a 28-year-old male weight lifter who died suddenly while driving a bicycle. Forensic autopsy and histopathological examinations revealed granulomatous lesions in the myocardium and hilar lymph nodes. The latter had massive caseation necrosis, epithelioid granulomas and Langhans' giant cells suggestive of tuberculosis. However, the myocardium showed predominantly multinucleated foreign body and myogenic giant cells, lymphocytes, plasma cells, macrophages, eosinophils. Staining for acid-fast bacilli was negative. The present case highlights the difficulty in establishing whether the granulomatous lesions in the hilar lymph nodes and the myocardium are incidental findings or whether they are related by the same pathogenetic mechanisms.