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Chinese Journal of Digestive Endoscopy ; (12): 569-571, 2011.
Artículo en Chino | WPRIM | ID: wpr-419990

RESUMEN

Objective To investigate the clinical characteristics of fundic gland polyps (FGPs).Methods Data of patients with FGPs diagnosed from January 2005 to May 2010 were collected and retrospectively analyzed.Results A total of 485 patients were found to have FGPs during routine upper endoscopy,accounting for 0.6% of total upper endoscopy examinations at the same time period.It was most frequently seen in middle aged females.Clinical symptoms included abdominal distention and discomfort ( 182/485,37.5% ),gastroesophageal reflux symptoms ( 83/485,17.1% ) and upper abdominal pain (102/485,21.0% ).51.3% (249) of the polyps were located at fundus and 168 (34.6% ) were at corpus,with most of FGPs (62.3%,302/485) were single polyp with broad base (less than 5mm),and 22.7% (110/485 ) were multiple ones scattering throughout the fundus.The pathology typically showed cystic lesions in the fundic glands,with dysplasia in 8 and intestinal metaplasia in 3,accompanied by duodenal polyps in 11 and gastric cancer in 1.H.pyloriinfection was detected in 47.8 % subjects which was similar to the rate of general population (56.1% ) in the same period (P =0.422 ).In addition,immunohistochemisty staining for adenomatous polyposis coli and cyclooxygenase-2 was performed in 12 patients,which showed all polyps were positive for adenomatous polyposis coli and 9 of them were cyclooxygenase-2 positive.Conclusion FGPs may not be correlate to H.pyloriinfection.It can be accompanied by dysplasia,intestinal metaplasia and duodenal polyps.Pathological and immunohistochemical studies may promote a better understanding and standardized diagnosis and treatment for this disease.

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