RESUMEN
Histopathological changes were observed in liver, kidney and muscles of normal, protein-malnourished, diabetic as well as both protein-malnourished and diabetic albino rats when exposed to a mixture of monocrotophos, hexachlorocyclohexane and endosulfan at varying intervals. The examination revealed hepatotoxic, nephrotoxic and muscular necrotic effects in pesticides exposed rats. Toxicity was aggravated in protein-malnourished and diabetic animals and more so, if the animals were both diabetic and protein-malnourished.
Asunto(s)
Animales , Diabetes Mellitus/patología , Endosulfano/farmacología , Femenino , Riñón/efectos de los fármacos , Hexaclorociclohexano/farmacología , Hígado/efectos de los fármacos , Masculino , Desnutrición/patología , Monocrotofos/farmacología , Músculos/efectos de los fármacos , Plaguicidas/farmacología , Ratas , Ratas WistarRESUMEN
The quality of extruded faba bean (EFB) (Vicia faba L.) as a protein supplement in cereals diet was evaluated. Growth rate and protein efficiency ratio was better in 20% EFB blended dietary group of rats than those fed either on cereals alone or at 40% EFB supplementation. Subsequent studies on digestibility co-efficient, biological value, net protein utilization and net protein ratio also confirmed biological utilization of EFB proteins in a better way at low level (20%).