Intrahepatic Biliary Papillomatosis

Biliary papillomatosis (BP) is an extremely rare condition that's characterized by multicenteric proliferations of adenomatous epithelium within the large bile ducts. Although BP is basically a collection of benign papillary adenoma, papillary adenocarcinoma can develop within these lesions, and it has a tendency to spread supericially along the bile duct mucosa. Such a malignancy is rare, but the prognosis is poor if it is impossible to completely remove the tumor. We report here on one case of multiple biliary papillomatosis in the biliary tree.