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An. acad. bras. ciênc ; 72(2): 173-86, Jun. 2000.
Artículo en Inglés | LILACS | ID: lil-262041

RESUMEN

The interaction between each one of Trichomonas vaginalis and Tritrichomonas foetus with their hosts is a complex process in which components associated to the cell surfaces of both parasites and host epithelial cells, and also to soluble components found in vaginal/urethral secretions, are involved. Either cytoadhesion or the cytotoxicity exerted by parasites to host cells can be dictated by virulence factors such as adhesins, cysteine proteinases, laminin-binding proteins, integrins, integrin-like molecules, a cell detachment factor, a pore-forming protein, and glycosidases among others. How trichomonads manipulate informations from the extracellular medium, transduce such informations, and respond to them by stimulating the activities of some surface molecules and/or releasing enzymes are the aspects concerning trichomonal virulence which are here briefly reviewed and discussed.


Asunto(s)
Humanos , Animales , Masculino , Femenino , Transducción de Señal/fisiología , Tricomoniasis/diagnóstico , Trichomonas/fisiología , Células Epiteliales , Matriz Extracelular , Interacciones Huésped-Parásitos/fisiología , Hierro/fisiología , Trichomonas vaginalis/citología , Trichomonas vaginalis/patogenicidad , Trichomonas vaginalis/fisiología , Trichomonas/citología , Trichomonas/patogenicidad , Sistema Urogenital/parasitología
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