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Rev. med. Chile ; 150(6): 828-831, jun. 2022. ilus
Artículo en Español | LILACS | ID: biblio-1424126

RESUMEN

Renal involvement in COVID-19 infection is varied and worsens its outcome and prognosis. However, the association of COVID-19 infection with glomerulonephritis is exceptional. We report a 46-year-old woman with COVID-19 who had an acute kidney injury and ANCA associated glomerulonephritis two weeks after the onset of the disease. The kidney biopsy showed a crescentic glomerulo-nephritis and the presence of anti-glomerular basement membrane antibodies (GBM-Abs). She was treated with steroids and oral cyclophosphamide with good response without requiring plasmapheresis. Plasma anti GBM-Abs were negative. This case suggests that the presence of anti-GBM-Abs in the kidney, was temporally related to COVID-19 pulmonary damage. The absence of plasma antibodies is probably due to transient production and glomerular adsorption, but with unknown pathogenic role.


Asunto(s)
Humanos , Femenino , Persona de Mediana Edad , COVID-19/complicaciones , Glomerulonefritis/complicaciones , Autoanticuerpos , Membrana Basal/patología , Anticuerpos Anticitoplasma de Neutrófilos
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