Gastrointestinal Basidiobolomycosis mimicking colon cancer in a Sudanese patient

Basidiobolomycosis is a rare disease caused by the fungus Basidiobolus ranarum. The incidence Rate of Gastrointestinal Basidiobolomycosis is approximately 1 in 45,333,334 or 0.00% in every 5 people in USA], member of the class Zygomycetes found worldwide [1].Basidiobolomycosis is usually a subcutaneous infection but rarely gastrointestinal1. This fungus is found mainly in the soil and on decaying vegetations2. It has been isolated from the banks of tropical rivers in West Africa, and has also been found in association with some insects2. The fungus is known to be present in the gastrointestinal tracts of reptiles, amphibians, and some bat species3. Definitive diagnosis requires culture and serological testing may be helpful. The fungal morphology and the Splendore-Hoeppli phenomenon are characteristic histological features. Basidiobolomycosis is treated with surgical resection and itracanzole 200mg BD for three months or Amphotericin B 5mg /kg iv/24 hrs4

Cutaneous leishmaniasis in Sudan: an update

Cutaneous leishmaniasis due to L.major is now endemic in many parts of the northern Sudan. In this up-date we discuss the clinical manifestations of cutaneous leishmaniasis, its diagnosis and treatment. The most common clinical forms are nodular, noduloulcerative and ulcerative lesions. Less common forms are sporotrichoid lesions, leishmanial dactylitis, leishmanial cheilitis, mycetoma- and residivans-like types. In a suspected case the diagnosis is made by demonstration of leishmania parasites in slit smears or biopsy, isolation of the parasite by culture in appropriate media and by the polymerase chain reaction [PCR] using specific primers. The majority of lesions heal spontaneously. Criteria for local or systemic treatment are given

unusual case of mucosal leishmaniasis with cutaneous dissemination in Sudan and its epidemiological significance

Sudan is endemic for visceral, cutaneous and mucosal leishmaniasis. The latter is the least common of the three forms of leishmaniasis. It is caused by L. donovani, the same parasite that causes visceral leishmaniasis [VL] in the country. Most of the cases were reported from VL endemic areas, the majority in adults. The disease may be primary in the oral and or the upper respiratory mucosa or may follow or accompany visceral leishmaniasis. This paper is a report of a case of mucosal leishmaniasis of the nose and lips. It is unusual in several aspects: the disease was acquired in a village where no cases of VL or mucosal leishmaniasis were recorded within living memory, before an outbreak in 1981 during which the patient was infected; the patient was infected at the age of five years and the disease remained active for 22 years causing physical deformity and psychological trauma to the patient

Blue nevus developing in a keratin cyst: a case report

A 35 years old patient reported with a ten years history of a cystic mass involving the skin and subcutaneous tissue over the shoulder. The cyst proved to be a keratin cyst with a blue nevus in its wall. This is an example of a group of lesions known as nevus with cyst, a term applied to different types of cysts that are closely associated anatomically with a melanocytic nevus