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1.
Audiol., Commun. res ; 28: e2740, 2023. tab, graf
Artículo en Portugués | LILACS | ID: biblio-1439467

RESUMEN

RESUMO O objetivo deste estudo foi relatar a abordagem interdisciplinar no manejo da macroglossia em um caso de paciente com síndrome de Beckwith-Wiedemann, no período de dez anos. O acompanhamento iniciou pela equipe de Cirurgia Bucomaxilofacial, seguido da Fonoaudiologia, em função de dificuldades alimentares. Após avaliação clínica e instrumental, aos 8 meses de idade, iniciou-se a intervenção fonoaudiológica com foco na disfagia orofaríngea e na terapia miofuncional orofacial. Foi verificado, com 1 ano e 11 meses, ausência de sinais de alteração de deglutição em fase faríngea e melhora na postura de lábios e língua. Aos 3 anos, foram iniciados estímulos para retirada dos hábitos orais e o treino da função mastigatória. O tratamento ortodôntico para correção de mordida aberta anterior e mordida cruzada posterior unilateral iniciou-se aos 6 anos. Aos 7 anos e 5 meses de idade, constatou-se estabilidade do modo respiratório nasal e adequação da postura de repouso de lábios e língua. Aos 9 anos, em função de recidiva das alterações oclusais, optou-se pela redução cirúrgica da língua seguida de terapia miofuncional orofacial, retomada aos 9 anos e 3 meses. O resultado foi a correção da postura da língua na deglutição e a adequação da fala. A associação dos tratamentos, envolvendo Fonoaudiologia, Ortodontia e Cirurgia Bucomaxilofacial foi considerada efetiva no manejo da macroglossia, resultando na adequação e equilíbrio das funções orofaciais.


ABSTRACT This study aims to report the interdisciplinary management of macroglossia in a Beckwith-Wiedemann syndrome patient during ten years. Clinical follow-up started by the Oral and Maxillofacial Surgery team, followed by Speech Therapy due to feeding difficulties. After clinical and instrumental evaluation, at 8 months old, the speech therapy intervention was indicated, focusing on oropharyngeal dysphagia and orofacial myofunctional therapy. At 1 year and 11 months, no signs of swallowing alteration in the pharyngeal phase and improvement in the posture of the lips and tongue were found. At the age of 3, stimulation to remove oral habits and train masticatory function were initiated. Orthodontic treatment to correct anterior open bite and unilateral posterior crossbite started at age 6. At 7 years and 5 months, there was stability in the nasal breathing mode and adequacy of resting posture of lips and tongue. At the age of 9, due to relapse of the occlusal alterations, surgical reduction of the tongue was indicated, followed by orofacial myofunctional therapy, restarted at the age of 9 years and 3 months. The result was the correction of the posture of the tongue during swallowing and speech adequacy. The association of treatments involving Speech Therapy, Orthodontics and Oral and Maxillofacial Surgery was considered effective in the management of the macroglossia. It resulted in the adequacy and equilibrium of orofacial functions.


Asunto(s)
Humanos , Masculino , Niño , Grupo de Atención al Paciente , Síndrome de Beckwith-Wiedemann/diagnóstico , Terapia Miofuncional/métodos , Glosectomía , Macroglosia/terapia , Ortodoncia , Fonoaudiología
2.
J. appl. oral sci ; 25(1): 10-19, Jan.-Feb. 2017. tab, graf
Artículo en Inglés | LILACS, BBO | ID: biblio-841166

RESUMEN

Abstract Objectives This study aimed to evaluate the potential of adipose-derived stem cells (ASCs) combined with a modified α-tricalcium phosphate (α-TCP) or gelatin sponge (GS) scaffolds for bone healing in a rat model. Material and Methods Bone defects were surgically created in the femur of adult SHR rats and filled with the scaffolds, empty or combined with ASCs. The results were analyzed by histology and histomorphometry on days seven, 14, 30, and 60. Results Significantly increased bone repair was observed on days seven and 60 in animals treated with α-TCP/ASCs, and on day 14 in the group treated with GS/ASCs, when compared with the groups treated with the biomaterials alone. Intense fibroplasia was observed in the group treated with GS alone, on days 14 and 30. Conclusions Our results showed that the use of ASCs combined with α-TCP or GS scaffolds resulted in increased bone repair. The higher efficacy of the α-TCP scaffold suggests osteoconductive property that results in a biological support to the cells, whereas the GS scaffold functions just as a carrier. These results confirm the potential of ASCs in accelerating bone repair in in vivo experimental rat models. These results suggest a new alternative for treating bone defects.


Asunto(s)
Animales , Masculino , Materiales Biocompatibles/farmacología , Regeneración Ósea/efectos de los fármacos , Fosfatos de Calcio/farmacología , Tejido Adiposo/citología , Trasplante de Células Madre/métodos , Andamios del Tejido , Esponja de Gelatina Absorbible/farmacología , Osteogénesis/efectos de los fármacos , Ratas Endogámicas SHR , Sales de Tetrazolio , Factores de Tiempo , Cicatrización de Heridas/efectos de los fármacos , Materiales Biocompatibles/uso terapéutico , Fosfatos de Calcio/uso terapéutico , Adhesión Celular/efectos de los fármacos , Células Cultivadas , Reproducibilidad de los Resultados , Resultado del Tratamiento , Modelos Animales , Proliferación Celular/efectos de los fármacos , Fémur/cirugía , Fémur/patología , Fibroblastos/efectos de los fármacos , Formazáns , Esponja de Gelatina Absorbible/uso terapéutico
3.
J. appl. oral sci ; 24(2): 162-170, Mar.-Apr. 2016. tab, graf
Artículo en Inglés | LILACS | ID: lil-779902

RESUMEN

ABSTRACT The understanding of bone repair phenomena is a fundamental part of dentistry and maxillofacial surgery. Objective The present study aimed to evaluate the influence of buried magnetic field stimulation on bone repair in rat calvaria after reconstruction with autogenous bone grafts, synthetic powdered hydroxyapatite, or allogeneic cartilage grafts, with or without exposure to magnetic stimulation. Material and Methods Ninety male Wistar rats were divided into 18 groups of five animals each. Critical bone defects were created in the rats’ calvaria and immediately reconstructed with autogenous bone, powdered synthetic hydroxyapatite or allogeneic cartilage. Magnetic implants were also placed in half the animals. Rats were euthanized for analysis at 15, 30, and 60 postoperative days. Histomorphometric analyses of the quantity of bone repair were performed at all times. Results These analyses showed significant group by postoperative time interactions (p=0.008). Among the rats subjected to autogenous bone reconstruction, those exposed to magnetic stimulation had higher bone fill percentages than those without magnetic implants. Results also showed that the quality of bone repair remained higher in the former group as compared to the latter at 60 postoperative days. Conclusions After 60 postoperative days, bone repair was greater in the group treated with autogenous bone grafts and exposed to a magnetic field, and bone repair was most pronounced in animals treated with autogenous bone grafts, followed by those treated with powdered synthetic hydroxyapatite and allogeneic cartilage grafts.


Asunto(s)
Animales , Masculino , Regeneración Ósea/fisiología , Trasplante Óseo/métodos , Magnetoterapia/métodos , Campos Magnéticos , Cráneo/cirugía , Factores de Tiempo , Distribución Aleatoria , Reproducibilidad de los Resultados , Resultado del Tratamiento , Ratas Wistar , Durapatita/uso terapéutico , Sustitutos de Huesos/uso terapéutico
4.
RFO UPF ; 18(1)jan.-abr. 2013.
Artículo en Portugués | LILACS | ID: lil-696454

RESUMEN

Objectives: to compare the reproducibility of Puricelli's panorametry on conventional panoramic radiography and on CBCT reformatted panoramic images, acquired in MIP mode. This study also compared linear and angular measurements between both exams. Methods: were evaluated 54 pairs of conventional panoramic radiography and CBCT panoramic MIP reconstructions. panorametry was manually traced, in both films, by three examiners. The originally proposed linear and angular, dental and skeletal measurements where tabulated and compared between imaging methods. Inter-examiner reproducibility was tested by intraclass correlation coefficient, and the differences between measurements of both methods were analyzed by Student?s t test. Results: the inter-examiner correlation was high for both the conventional panoramic radiography and CBCT panoramic MIP reconstructions (0.86±0.07 and 0.88±0.07, respectively). Total magnification of pano-ramic radiograph, for the studied measurements, was of 4.3%, being vertically higher (12%) and to the horizontal inferior line (11.5%) comparing to the angular measurements of straight lines (6.7%) and to the horizontal superior lines (1.9%). The conventional panoramic radiography, in comparison to the CBCT, presented lower values for most angular measurements. Conclusions: Puricelli?s panorametry presents a high degree of reproducibility in both conventional panoramic radiography and CBCT reformatted panoramic images. Conventional panoramic radiography presents augmented linear and angular skeletal measurements and reduced dental angular measurements when compared to CBCT reformatted panoramic images. Conventional panoramic radiographs seem to present a consistent augmentation of the right side of the mandibular image.

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