RESUMEN
Parkinson's disease presents its particular complications and others associated with pharmacological therapy. In this report we present an 80 year-old patient with Parkinson's disease, who having a febrile syndrome decides to suspend his usual antiparkinsonian treatment. As a consequence an exacerbation of their extrapyramidal symptoms appear and his fever syndrome persists without infectious focus. Neuroleptic Malignant Syndrome variant with fatal outcome was concluded.
La Enfermedad de Parkinson presenta complicaciones propias de su patología y asociadas a su terapia farmacológica. Presentamos un paciente de 80 años con Enfermedad de Parkinson, que debuta con un síndrome febril por lo que suspende su tratamiento antiparkinsoniano habitual. Como consecuencia, se agrega exacerbación de su clínica extrapiramidal, persistiendo su cuadro febril sin foco infeccioso. Se concluye variante del Síndrome Neuroléptico Maligno con resolución fatal.