Severity of erectile dysfunction is highly correlated with the syntax score in patients undergoing coronariography

ABSTRACT Objective To investigate the association between the severity of erectile dysfunction (ED) and coronary artery disease (CAD) in men undergoing coronary angiography for angina or acute myocardial infarct (AMI). Material and Methods We studied 132 males who underwent coronary angiography for first time between January and November 2010. ED severity was assessed by the international index of erectile function (IIEF-5) and CAD severity was assessed by the Syntax score. Patients with CAD (cases) and without CAD (controls) had their IIEF-5 compared. In the group with CAD, their IIEF-5 scores were compared to their Syntax score results. Results We identified 86 patients with and 46 without CAD. The IIEF-5 score of the group without CAD (22.6±0.8) was significantly higher than the group with CAD (12.5±0.5; p<0.0001). In patients without ED, the Syntax score average was 6.3±3.5, while those with moderate or severe ED had a mean Syntax score of 39.0±11.1. After adjustment, ED was independently associated to CAD, with an odds ratio of 40.6 (CI 95%, 14.3-115.3, p<0.0001). The accuracy of the logistic model to correctly identify presence or absence of CAD was 87%, with 92% sensitivity and 78% specificity. The average time that ED was present in patients with CAD was 38.8±2.3 months before coronary symptoms, about twice as high as patients without CAD (18.0±5.1 months). Conclusions ED severity is strongly and independently correlated with CAD complexity, as assessed by the Syntax score in patients undergoing coronariography for evaluation of new onset coronary symptoms.

Urine leak in minimally invasive partial nephrectomy: analysis of risk factors and role of intraoperative ureteral catheterization

Purpose To investigate risk factors for urine leak in patients undergoing minimally invasive partial nephrectomy (MIPN) and to determine the role of intraoperative ureteral catheterization in preventing this postoperative complication. Materials and Methods MIPN procedures done from September 1999 to July 2012 at our Center were reviewed from our IRB-approved database. Patient and tumor characteristics, operative techniques and outcomes were analyzed. Patients with evidence of urine leak were identified. Outcomes were compared between patients with preoperative ureteral catheterization (C-group) and those without (NC-group). Univariable and multivariable analyses were performed to identify factors predicting postoperative urine leak. Results A total of 1,019 cases were included (452 robotic partial nephrectomy cases and 567 laparoscopic partial nephrectomy cases). Five hundred twenty eight patients (51.8%) were in the C-group, whereas 491 of them (48.2%) in the NC-group. Urine leak occurred in 31(3%) cases, 4.6% in the C-group and 1.4% in the NC-group (p<0.001). Tumors in NC-group had significantly higher RENAL score, shorter operative and warm ischemic times. On multivariable analysis, tumor proximity to collecting system (OR=9.2; p<0.01), surgeon’s early operative experience (OR=7.8; p<0.01) and preoperative moderate to severe CKD (OR=3.1; p<0.01) significantly increased the odds of the occurrence of a postoperative urine leak. Conclusion Clinically significant urine leak after MIPN in a high volume institution setting is uncommon. This event is more likely to occur in cases of renal masses that are close to the collecting system, in patients with preoperative CKD and when operating surgeon is still in the learning curve for the procedure. Our findings suggest that routine intraoperative ureteral catheterization during MIPN does not reduce the probability of postoperative urine leak. In addition, it adds to the overall ...

Step-by-Step robotic heminephrectomy for duplicated renal collecting system

Introduction A duplicated renal collecting system is a relatively common congenital anomaly rarely presenting in adults. Aim In this video we demonstrate our step-by-step technique of Robotic heminephrectomy in a patient with non-functioning upper pole moiety. Materials and Methods Following cystoscopy and ureteral catheter insertion the patient was placed in 600 modified flank position with the ipsilateral arm positioned at the side of the patient. A straight-line, three arm robotic port configuration was employed. The robot was docked at a 90-degree angle, perpendicular to the patient. Following mobilization the colon and identifying both ureters of the duplicated system, the ureters were followed cephalically toward, hilar vessels where the hilar anatomy was identified. The nonfunctioning pole vasculature was ligated using hem-o-lok clips. The ureter was sharply divided and the proximal ureteral stump was passed posterior the renal hilum. Ureteral stump was used as for retraction and heminephrectomy is completed along the line demarcating the upper and lower pole moieties. Renorrhaphy was performed using 0-Vicryl suture with a CT-1 needle. The nonfunctioning pole ureter was then dissected caudally toward the bladder hiatus, ligated using clips, and transected. Results The operating time was 240 minutes and blood loss was 100 cc. There was no complication post-operatively. Conclusions Wrist articulation and degree of freedom offered by robotic platform facilitates successful performance of minimally invasive heminephrectomy in the setting of an atrophic and symptomatic renal segment. .

Disfunção erétil: um marcador precoce de doenças cardiovasculares / Erectile dysfunction: an early marker of cardiovascular diseases

A disfunção erétil tem fatores de risco similares aos das doenças cardiovasculares, mas também pode ser um fator de risco independente para tais doenças. As evidências atuais consideram a disfunção erétil como uma desordem primordialmente de origem vascular e, mais do que isso, como um marcador precoce das doenças cardiovasculares. Apesar disso, o potencial da disfunção erétil como um sinal para alertar os médicos para uma possível manifestação precoce de doenças cardiovasculares mais graves tem sido pouco explorado na prática clínica diária.

A importância da antibioticoprofilaxia nas herniorrafias inguinais / The importance of antibiotic prophylaxis in inguinal herniorraphies

de antibióticos profiláticos a fim de reduzir os índices de infecção da ferida operatória permanece como motivo de análise. O objetivo do presente estudo é analisar o benefício da antibioticoprofilaxia no reparo das hérnias, refletindo na redução da morbidade do paciente e dos custos hospitalares. Material e método: Foram analisados, prospectivamente, 120 pacientes submetidos a herniorrafias inguinais no Complexo Hospitalar Santa Casa de Porto Alegre, com um acompanhamento pós-operatório de 3 meses. Desses, 19 pacientes foram excluídos do estudo por não comparecerem às consultas de acompanhamento. Os pacientes foram divididos em 2 grupos, com e sem o uso de cefalotina endovenosa 1h antes da herniorrafia. Os grupos foram semelhantes quanto às variáveis analisadas. Resultados: Um total de 12 pacientes (12,1%) apresentou infecção na ferida operató- ria. Verificou-se maior índice de infecção no grupo sem antibioticoprofilaxia (14,6% contra 9,4%); no entanto, esta diferença não foi significativa (p>0,05). Conclusões: Nosso estudo, bem como a literatura, não permite concluir quanto à eficácia da antibioticoprofilaxia no reparo das hérnias inguinais (AU)

Background: Nowadays herniorraphies are surgical procedures widely performed. The use of prophylatic antibiotics with the goal to reduce infection rates at the wound remains as a matter of discussion. This study analises the benefits of antibioticprophylaxis on hernia repair, concerning reduction in both morbidity and hospital expenses. Method: One hundred and twenty patients who have undergone inguinal herniorraphies at the Santa Casa Hospital Complex of Porto Alegre were analised prospectively, with a 3-month postoperative follow-up period. Nineteen pacients were excluded from the study because of lack of follow-up. Patients were divided in 2 groups: with and without the use of intravenous Cefalotine 1g, one hour before the procedure. Groups were similar as for the variables analised. Results: A total of 12 (12,1%) patients presented with wound infections. A higher infection rate was verified in the group without antibioticprophylaxis (14,6% against 9,4%), however this diference wasn't significative (p>0.05). Conclusions: Our study, just as the literature, does not allow one to conclude about the antibioticprophylaxis efficacy in inguinal hernia repairs (AU)

Estudo comparativo entre anestesia local e raquianestesia na herniorrafia inguinal / Comparative study between local and spinal anesthesia in inguinal herniorraphy

Objetivo: Apesar das vantagens da anestesia local para o reparo de hérnias inguinais já estarem bem estabelecidas, a técnica anestésica mais utilizada em nosso meio é a raquidiana. O objetivo deste estudo é investigar os benefícios do emprego da anestesia local nas herniorrafias inguinais, comparando aspectos relacionados a dor, consumo de analgésicos, encargos hospitalares e satisfação do paciente. Métodos: Foram analisados prospectivamente 105 pacientes submetidos a herniorrafias inguinais eletivas no período de janeiro a outubro de 2002, no Complexo Hospitalar Santa Casa de Porto Alegre. Quatorze pacientes foram excluídos. A amostra final foi dividida em dois grupos: um submetido à anestesia raquidiana (69 pacientes) e o outro à anestesia local com sedação endovenosa (22 pacientes). Resultados: O grupo da anestesia local teve maior incidência de dor no transoperatório (p<0,05). No entanto, durante a internação hospitalar este grupo apresentou menor incidência e intensidade de dor (p<0,05), consumindo quantidades semelhantes de analgésicos (p>0,05). Além disso, encontramos no grupo da anestesia local menor tempo de permanência na sala de recuperação (p<0,05) e custos anestésicos 62,45% menores em cada procedimento. A dor no transoperatório, na anestesia local, não prejudicou a satisfação do paciente em relação à técnica anestésica (p>0,05). Conclusões: A anestesia local com sedação mostrou-se adequada para ser utilizada nas herniorrafias inguinais primárias. Ela apresentou vantagens em relação à anestesia raquidiana: menor intensidade de dor, menor tempo de recuperação anestésica e menores custos hospitalares (AU)

Background: Advantages of local anesthesia for inguinal hernia repair are well established. Even though, the spinal anesthetic technique is still the routine in our hospitals. The objective of this study is to compare the use of local and spinal anesthetic techniques for inguinal herniorraphies. We evaluated the repercussion of these anesthetic techniques in pain, use of analgesic medications, hospital discharges and satisfaction with the procedure. Methods: One hundred and five patients who underwent elective inguinal herniorraphy between January and October, 2002, were prospectively analyzed. Fourteen patients were excluded. The amount of patients was divided in two groups: spinal anesthesia (69 patients) and local anesthesia with sedation (22 patients). Results: Local anesthesia group presented greater pain incidence during the transoperative period (p<0.05). Despite this, while in hospital, these patients referred minor incidence and intensity of pain (p<0.05), with comparable consuming of analgesics (p>0.05). Besides, the local anesthesia group had a minor anesthesia recovery time (p<0.05) and an expense of 62,45% minor in each procedure. Pain related in the local anesthesia group during the surgery did not influence the grade of satisfaction with the procedure (p>0.05). Conclusions: Local anesthesia with sedation is an adequate anesthetic technique to be used in primary inguinal herniorraphies. It showed advantages over spinal anesthesia: lower incidence and intensity of pain during hospital staying, shorter anesthesia recovery time and minor hospitals expenses (AU)