Development of high performance liquid Chromatographic Fingerprint of cerebroprotein hydrolysate and its injection / 中国药学杂志

OBJECTIVE: To establish the specific chromatogram of cerebroprotein hydrolysate and so asto provide an effective way for the quality control and process evaluation of cerebroprotein hydrolysate and its injection.

Study on preparation and standardization of reference standard of chondroitin substance sodium / 中国药学杂志

OBJECTIVE: to establish a national reference substance for chondroitin sulfate sodium. METHODS: Identification of chondroitin sulfate sodium was carried out by infrared(IR) and high performance liquid chromatography(HPLC). A high performance size exclusion chromatography in conjunction with refractive index detector and multi-angle laser light scatter(MALLS) was used to determine the molecular weight and molecular weight distribution of chondroitin sulfate sodium. The content of chondroitin sulfate sodium was calculated by mass balance method. RESULTS: The content of chondroitin sulfate sodium reference substance was 99.1%. CONCLUSION: The establishment of national reference substance of chondroitin sulfate sodium can effectively control the quality of the product. Copyright 2012 by the Chinese Pharmaceutical Association.