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Chinese Journal of Primary Medicine and Pharmacy ; (12): 1057-1058,倒插1, 2008.
Artículo en Chino | WPRIM | ID: wpr-569980

RESUMEN

Objective To assess the effects of thalidomide on VEGF mRNA level in human breast cancer cell lines. Methods Breast cancer cells were treated with thalidomide for 24~72h, RT-PCR was uced to detect the level of VEGF mRNA expression. Results When the concentration of drug is 50μg/L,thalidomide strongly inhibited the level of VEGF mRNA expression. Conclusion Within certain concentration range of thalidomide can inhibit the level of VEGF mRNA expression in breast cancer cell.

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