Application Status of Phytotherapy for Prevention and Treatment of Chemotherapy Induced Phlebitis / 中国中医药信息杂志

Chemotherapy induced phlebitis is a kind of acute and local inflammation caused by chemotherapeutics, which has complicated factors. There are many prevention measures. One of them is phytotherapy, which is widely used as a part of natural therapy. This article summarized the phytotherapy used for chemotherapy induced phlebitis, with the purpose to provide the references for enhancing the clinical intravenous administration and ensuring the smooth progress of chemotherapy.

Gallbladder sarcomatoid carcinoma:six cases and literature review / 中国肿瘤临床

Objective: To investigate the clinicopathological features, diagnosis, and differential diagnosis of gallbladder sarcomatoid carcinoma. Methods: The clinical manifestations and the microscopic and immunohistochemical characteristics of six patients with gallbladder sarcomatoid carcinoma were analyzed with a follow-up period. Related literature was reviewed. Results:Immunohistochemical markers of gallbladder sarcomatoid carcinoma with spindle cell morphology were epithelial and mesenchymal positivity. Conclusion: Gallbladder sarcomatoid carcinoma could be firmly diagnosed by microscopic morphology and immunohistochemistry. Radical resection is currently used to treat such patients. However, more cases with longer follow-up period are needed to discover better treatments and improve the survival of these patients.

Expression and significance of autophagic gene Beclin 1 and MAP1 LC3 protein in cutaneous malignant melanoma / 临床与实验病理学杂志

Purpose To detect the expression of autophagic genes Beclin 1 and MAP1LC3 in cutaneous malignant melanoma and to ex-plore the relationship between autophagia and malignant melanoma. Methods 85 cases of speicmens including normal skin tissue, in-tradermal nevi, radial growth phase melanomas, vertical growth phase melanomas, and metastatic melanoma were collected, and the protein expression of Beclin 1 and MAP1LC3 were evaluated by immunohistochemistry of SP methods. Results The Beclin 1 and MAP1LC3 expression were pretended to be 100% in normal skin tissue, and they were declined to 85% and 95% in intradermal nevi, 58% and 50% in radial growth phase melanomas, 49. 5% and 44. 4% in vertical growth phase melanomas, both of 17% in melanoma metastases (P<0. 05). Conclusion Beclin 1 and MAP1LC3 autophagic gene expression were significantly decreased with tumor pro-gression, as well as was correlated with conventional histopathologic prognostic factors.