Acquired perforating dermatosis in a patient with chronic renal failure

Abstract Perforating dermatoses are a group of skin diseases characterized by transepidermal elimination of dermal material. The disease is divided into two groups: the primary group and the secondary group. The classical or primary perforating dermatoses are subdivided into four types according to the eliminated dermal materials: Kyrle disease, perforating reactive collagenosis, elastosis perforans serpiginosa, and perforating folliculitis. The secondary form is known as acquired perforating dermatosis. The term was proposed in 1989 by Rapini to designate the perforating dermatoses affecting adult patients with systemic disease, regardless of the dermal materials eliminated. This report describes a case of the disease with elimination of collagen and elastic fibers in a patient with chronic renal failure.

Case for diagnosis

Degos disease, also known as malignant atrophic papulosis, is a rare occlusive vasculopathy of unknown etiology characterized by infarcts in the dermis, gastrointestinal tract, central nervous system, and other organs. It is characterized by papules, which become umbilicated and evolve with a depressed porcelain-white central area, with an erythematous halo with telangiectasias. Histological findings include wedge-shaped dermoepidermal necrosis and blood vessel thrombosis. Approximately 50-60% of patients with systemic symptoms die within 2-3 years, most due to gastrointestinal perforation. We report a typical case, with lethal outcome, in a 45-year-old woman.

Tratamento do molusco contagioso generalizado com ácido tricloroacético (ATA) num paciente com vírus da imunodeficiência adquirida (HIV): relato de caso / Generalized molluscum contagiosum in an HIV (human immunodeficiency virus) infected patient treated with topical trichloroacetic acid (TCA): case report

Os autores relatam o caso de um paciente HIV-positivo, portador de molusco contagioso disseminado, tratado com aplicação tópica de ácido tricloroacético, com bom resultado. Discutem-se aspectos epidemiológicos, clínicos e terapêuticos da infecção do molusco contagioso nos imunocompetentes e imunodeprimidos.