RESUMEN
Objective To observe the relationship between thyroid hormone levels and reduced pulmonary function in elderly male patients with chronic obstructive pulmonary disease(COPD).Methods One hundred and ninety-five cases of elderly male patients with COPD hospitalized from Jan 2006 to Feb 2010 were enrolled.Thyroid function and lung function(FEV1(forced expiratory volume in 1 second),FEV1/FVC(forced vital capacity))were examined routinely.Pulmonary function was compared between normal group(with normal thyroid function)and lower group(with thyroid hypofunction),thyroid function was also compared in patients with different grade levels(mild,moderate,severe,very severe)of pulmonary function.Results FEV1 and FEV1/FVC in thyroid hypofunction group were significantly decreased compared to the normal group(t =3.582,2.981,respectively,P ＜ 0.01).There was significant difference on T3,FT3 in patients with different grade levels of pulmonary function(F =1.959,1.873,respectively,P ＜ 0.05),among them,T3,FT3 were significantly different between mild group and severe group(P ＜ 0.05),but there was no significant difference in other groups(P ＞0.05).T4、FT4 、TSH displayed no significant difference in all groups(P ＞ 0.05).Conclusion Pulmonary function decreased obviously in elderly old male patients with COPD combined with thyroid hypofunction,and the lower level of thyroid hormone,the worse of pulmonary function.