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1.
Southeast Asian J Trop Med Public Health ; 2001 Jun; 32(2): 397-401
Artículo en Inglés | IMSEAR | ID: sea-33682

RESUMEN

Mycoplasma pneumoniae is increasingly recognized as an important cause of community acquired pneumonia (CAP) in children. We determined the importance of M. pneumoniae as a causative agent in 170 children aged 1 month to 15 years who were hospitalized with CAP over a 6-month period. The diagnosis of M. pneumoniae infection was based on serological evidence obtained by a particle agglutination test (SERODIA-MYCO II). A positive serological diagnosis was made if the acute phase serum titer was more than 1:160 or paired samples taken 2-4 weeks apart showed a four-fold or greater rise in the serum titer. M. pneumoniae was identified as the causative agent in 40 (23.5%) children. Children with M. pneumoniae infection were more likely to be older than 3 years (OR 4.0 95%CI 1.8-9.1, p<0.001), Chinese (OR 4.3 95%CI 2.0-8.9, p<0.001), have a duration of illness longer than 7 days prior to admission (OR 6.0 95%CI 2.7-13.5, p<0.001) and have perihilar interstitial changes on chest X-ray (OR 4.6 95%CI 2.2-9.9, p<0.001). A significant number of hospital admissions for CAP in Malaysian children can be attributed to M. pneumoniae. It is important to identify these children so as to administer the most appropriate antibiotic treatment.


Asunto(s)
Adolescente , Niño , Preescolar , Infecciones Comunitarias Adquiridas/diagnóstico , Femenino , Hospitalización , Humanos , Malasia/epidemiología , Masculino , Infecciones por Mycoplasma/diagnóstico , Mycoplasma pneumoniae/aislamiento & purificación , Neumonía Bacteriana/diagnóstico
2.
Southeast Asian J Trop Med Public Health ; 1993 Sep; 24(3): 467-71
Artículo en Inglés | IMSEAR | ID: sea-34438

RESUMEN

Eight cases of liver failure and encephalopathy were observed among twenty cases of grade 3 and grade 4 dengue hemorrhagic fever/dengue shock syndrome admitted to the Department of Pediatrics, University Hospital, Kuala Lumpur from January 1990 to December 1991. All patients with deterioriation in mental status showed a marked increase in liver enzymes (aspartate and alanine aminotransaminases) and severe coagulopathy. Six patients needed cerebral protection, including ventilation, intravenous sedation and muscle relaxants. There was one death during the period of study and one case of residual hemiparesis in a boy who had, in addition, intracerebral hemorrhage. All other survivors had complete recovery of liver and neurological function.


Asunto(s)
Alanina Transaminasa/sangre , Aspartato Aminotransferasas/sangre , Niño , Preescolar , Dengue/clasificación , Femenino , Fluidoterapia , Encefalopatía Hepática/sangre , Mortalidad Hospitalaria , Humanos , Incidencia , Lactante , Masculino , Tiempo de Tromboplastina Parcial , Tiempo de Protrombina , Respiración Artificial , Estudios Retrospectivos , Índice de Severidad de la Enfermedad , Choque Séptico/clasificación
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