1.
Cancer Research and Clinic
;
(6): 785-789, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-712904
RESUMEN
Pancreatitis is one of the important risk factors in the occurrence of pancreatic neoplasms. Several inflammation-related transcription factors and pathways have been confirmed to be involved in the carcinogenesis, but molecular mechanisms of pancreatitis-cancer transformation are still unclear, which largely limits the further development of potential anti-tumor drugs. Thus, it is important to figure out the underlying molecular mechanisms of pancreatitis-cancer transformation. This paper reviews the main biological characteristics, relevant important signaling pathways, clinical intervention strategies of pancreatitis-cancer transformation.