RESUMEN
Our work is a retrospective study about a series of 65 cases of ulcerative colitis [UC] collected during 3 years at the department of hepatogastroenterology in CHU Hassan II of Fes [Morocco]. The UC represented 2.1% of the hospitalizations and 73% of the inflammatory bowel disease. The mean age was 35 +/- 12 years [extremes from 16 to 70 years] with a female predominance. The diagnosis delay was on average 13.7 +/- 21.8 months. The principal symptom was the hemorrhagic diarrhoea [87.7%]. The endoscopy with the anatomopathologic study made it possible to pose the positive diagnosis of UC in 96% of the cases. The isolated rectal localization was observed in 14% of the cases, a pancolitis in 35.5% of the cases. The mainly polyarthralgic extraintesinal manifestations were noticed in 34% of the cases, but axial rheumatism was noted only in one case. The severity was appreciated by the score of Truelove and Witts, finding moderate desease [61.5%]. The oral corticosteroids were the drug more prescribed [67.7%], the intravenous way was necessary in 4.6% of the cases. The sulfasalazine was prescribed at 49.2% of the patients whereas the mesalamine was used in 33.8% of the cases. We had recourse to the azathioprine in 3 cases. The evolution of our patients was generally favorable with an average passing of 25.6 +/- 13.7 months. The objective of this study is to compare this series with the other national series in order to establish an idea first on the frequency of this affection in Morocco; and finally, to compare these data with those of the literature while insisting on the diagnostic difficulties which it can raise in current practice