[ effect of selective rhythmic movements on, hand- foot coordination in girl children with developmental coordination disorder]

Background and aim: Development Coordination Disorder [DCD] is occurred when the growth of motor skills delays or some difficulties emerge in performing coordinated movements that is led to the incidence of problems resulting inability to perform in daily tasks. The purpose of this study was to examine the effect of the selective rhythmic movements on hand - foot coordination of children with DCD

Methods: In this quasi experimental study, from a total of 475 girl children [6-11 years old] from Shahrekord city [Iran] 30 girl children were selected by the DSD questionnaire and Motor Observation Questionnaire for teachers. Lincolen - Osertsky Motor Proficiency Test was used to measure the dependent variables including hand- foot coordination. At first, subjects participated in pretest and then they were randomly divided into control and experimental groups. Selective Rhythmic Movements were performed by experimental group for eight weeks; three sessions per week and 45 minutes per- session. At the end of the period, both groups participated in the post test. The data were analyzed using independent study t- test

Results: Results showed that at pre-test conditions no significant difference was seen for the means of hand-foot coordination between experimental group vs. control group [P>0.05], but significant difference was observed between groups for post test values [P<0.01]

Conclusion: This study showed that selective rhythmic movements are led to hand- foot coordination improvement in DCD children

Pathogenicity and immunogenicity of native and mutant strains of Pasteurella multocida, the causative agents of haemorrhagic septicaemia

Haemorrhagic septicaemia [HS] is a fatal systemic disease of cattle and buffaloes. Some control is achieved with administration of alum-precipitated or oil-adjuvanted killed whole-cell vaccines injected subcutaneously. These vaccines, however, provide only short-term immunity and for effective use, they should be administered annually. We constructed an aroA attenuated derivative of a Pasteurella multocida serotype B:2 strain by allelic exchange of the native aroA sequence with aroA sequences disrupted with a kanamycin resistance cassette. This strain was confirmed to be aroA mutant by PCR. The aroA derivative was highly attenuated for virulence in a mouse model of HS and rabbits. Mouse and rabbit challenge experiments showed that i.p. or i.m. vaccination of an aroA strain completely protected mice or rabbits against challenge with a high dose [>1000 LD[50]] of the parent strain