[Immunological aspects of the kidney transplantation]

The immunological rejection is still, at the present time, a major risk in kidney transplantation. Accurate assessment of the immunological status of all patients awaiting transplantation or grafted, can assess this risk, this work is intended to describe, in the framework of kidney transplant from living donor, the role of the laboratory of histocompatibility in the immunological care and monitoring of patients: pre-transplant analysis, limitations and performance of available analysis techniques, criteria for matching pairs donor/recipient, follow-up of immunological post transplant. The last part will be devoted to the experience of the immunology unit at the blood transfusion service of ibn Sina Hospital in Rabat

[Interests of the assessment of non A non B hepatitis's indirects markers anti HBc and ALAT]

This is a study of the incidence of anti HBc and the seric rate of ALAT transaminases in the blood donors. The presence of the anti HBc has been searched by the ELISA technic in 4104 donors. Anti HBc was detected in 1358 [33,1%]. The HBs antigen has been searched to by ELISA technic and detected in 209 [5,1%] of the donors screened. This both markers, have been found in 134 [3,3%] donors. The seric rate of ALAT has been determined on 2627 serums by colorimetric method. 87[3,4%] donors had ALAT levels above 40 UI/I. The simultaneous study of presence of the anti-HBc and seric rate of ALAT has been realesed on 1754 serums. 25 [1,4%] of these donors have avered to be positive anti-HBc with raised ALAT. The HIV serology was negative for all the samples tested in hepatitis B virus serology. These results high light the importance of infection by hepatitis B virus in Morocco. Immunization measures against this virus would be desirables. however, for such a strategy, economic and epidemiological values need to be taken into consideration