RESUMEN
Objective: survey of antibiotic effects on serological titer of Mg and Ms infected broiler breeders
Design: observational study. Animals: A total of 42 ross broiler breeders
Procedure: thirty-six broiler breeders at 35 weeks old from an infected [Mg and Ms positive] poultry unit and six broiler breeders from a non-infected [Mg and Ms negative] poultry unit were kept in separated cages as recommended in Ross broiler breeder catalogue at the hospital of veterinary faculty of Urmia university. Blood samples were collected from broiler breeders in order to determine serological titers using rapid plate serum agglutination test [RPSAT] and ELISA, before and after administration of lincospectin, tiamulin, tylosin, ciprofloxacin and emofloxacin antibiotics for five days with recommended dosages of each antibiotics
Statistical analysis: SPSS statistical analysis program using ANOVA and Two tailed pair t-test were used to analyze the data
Results: the ELISA titers of the infected birds [within and among the groups] were differed significantly [P<0.05]. While ELISA titers of non-treated infected birds [group 6], increased significantly during this study but those of treated birds [groups 1-5], decreased indicating that overall, antibiotics such as lincospetin, tiamulin, tylosin, ciprofloxacin and emofloxacin reduced not only the severity of the infections but also their ELISA titers. Comparison of ELISA titers before and after treatment indicates that all antibiotics affect the overcome of the Mg and Ms infections but lincospectin, tiamulin and ciprofloxacin had the highest effect on both Mg and Ms ELISA titer while tylosin tartarat and,enrofloxacin had the lowest effect
Conclusion: antibiotics affect the outcome of the Mg and Ms infections in broiler breeders and reduce serological titers of Mg and Ms infected birds but do not clear the birds 6om the infections