RESUMEN
Objective: To assess the differences in relative risk of developing diabetes and CHD, obesity, fasting blood glucose, insulin and lipids of children having family history of diabetes or heart disease in first or second degree relatives as compared to control group
Design: Children were given a questionnaire to collect demographic data and to assess their dietary habits and family history. Anthropometric measurements and blood samples for fasting blood glucose, insulin and lipids of 8-10 years old children from 4 schools was taken
Setting: The samples of ninety-nine children were obtained to assess fasting blood glucose, insulin and lipids of children
Subjects: Children having positive family history of diabetes [n=44] or heart disease [n=16] in first or second degree relatives were compared with a control group [n=39]
Results: Children having positive family history for diabetes had slightly higher mean values for BMI, waist circumference, arm fat% as compared to the controls but the differences were not statistically significant. Overweight children [>85[th] Percentile of BMI for age] did not differ significantly in terms of various risk indicators however those who were in the uppermost tertile of arm fat% had significantly higher total Cholesterol, Triglycerides, LDL-C, LDL:HDL and Insulin levels [P<0.05 in each case]
Conclusion: Diabetes and CVD risks from positive family history for the disease are probably mediated through increased body fat percentage. Thus even when information about family history of disease is lacking, arm-fat-percentage could be used as an important screening tool for determining the risk status of children
RESUMEN
A community based diabetic survey was conducted in 1999, at Haji Zakaria Goth, Gaddap, near Baqai Medical University. The investigation was carried out to assess the prevalence of diabetes and its associated risk factors in the above location, with a view to start a community level diabetes management programme. The target population were both males and females above the age of 18 years. Two blood samples of all subject were taken; first for fasting and the second after two hours. A sample questionnaire was also filled for collecting demographic data. The anthropometric parameters such as blood pressure, weight and height were taken of all the subjects. Over all impaired glucose tolerance[JGT] was noted to be 4.4% and the prevalence of overall diabetes was 7.7% [newly diagnosed 4% known diabetes 3.7%].The setting up of a Diabetic Care Clinic will help to built a preventive frame work for diabetes management and prevention in Gaddap