RESUMEN
Background: Sulfur mustard [HD] [bis[2-chloroethyl] sulfide] is a strong alkylating agent with known mutagenic and suspected carcinogenic properties
Materials and Methods: 40 Albino-Nmari male rats, 3 months old , were divided into four groups [10 in each group] and injected with 5, 10 mg /kg sulfur mustard in tyrods buffer After 8 weeks rats were killed. The samples were fixed in formaldehyde solution [%10], stained with H and E and studied with light microscope
Results: Increased distance between seminiferous tubules. Accumulation of necrotic materials of the cells in the lumen of seminiferous, oligospermia, displacement of somniferous tubules and changing the situation of sertoli nuclei from the abdominal positioning to basal in both groups of sulfur mustard that compared with normal and tyrods groups
Conclusion: Presence of necrotic form of spermatocytes and necrotic cells with picnotic nuclei in both sulfur mustard groups but more in 10 mg/kg HD
RESUMEN
Background: Renal colic is a common cause of acute severe pain. Opioids and non-opioids analgesics and NSAIDs and phosphodiesterase enzyme [PDE] inhibitors are four medical cathegories that recommended for treatment, but the relative efficacy of these drugs is uncertain
Materials and Methods: To examine the benefits and disadvantages of pethidine, piralgin, diclofenac and aminophyllin for the management of pain in acute renal colic, as a randomised clinical trial study, patients with four suspected renal colic[n=200] were randomised to receive these 4-drugs at emergency ward of -hospitals. Pain relief and side effects was assessed at one hour after the analgesics. Datas has been analised by statistical soft ware of SPSS-ver.11
Results: pain reliefed in the pethidine group after 30 minute and one hour was %60 [30 patients] and %94 [47 patients], for piralgin group was %54 [27 patients] and %92 [46 patients], diclofenac group was %28 [14 patients]and %68 [34 patients] and for aminophylline was %24 [12 patients] and %62 [31 patients]. [P< 0/05] The side-effects of 4-groups was included: pethidine: nausea [11 Patients], vomiting [7 Patients], respiratory depression [3 Patients] and headache [2 Patients]; piralgin [3 Patients]; aminophylline: orthostatic hypothension [7Patients], vertigue [9 Patients], headache [1 2 patients]; diclofenac had no side-effect
Conclusion: Tramadol response was as same as pethidine but less side-effects. diclofenac is a good choice for mild pain; but aminophyllin had a bad response with very much side-effects
RESUMEN
Background: Human sperm heads which present disturbances of choranatin condensation are stained by acidic aniline blue. To determine whether the proportion of unstained heads, i.e with well condensed chromatin, can be considered as an index of sperm quality
Materials and Methods: stady was undertaken in 20 infertile patients with spinal cord injure and 20 infertile patients with non- spinal cord injure. In addition to the usual sperm characteristics, the percentages of unstained heads and of morphologically normal and abnormal forms were concomitantly evaluated
Results: The results obtained in this research show a significant relationship between the mean of sperm volume, concentration, validity and motility
Conclusion: In scipationts and the results taken by previous researchers. In addition the mean of sperm morphology and sperm condensation between the two groups was not significant so we can say that s.ci has no significant effected on condensation of chromatin of sperm
RESUMEN
Background: Sulfur mustard [HD] [bis[2-chloroethyl] sulfide] is a strong alkylating agent with known mutagenic and suspected carcinogenic properties
Materials and Methods: 40 Albino-Nmari male rats, 3 months old, were divided into four groups [10 in each group] and injected with 5 , 10 mg /kg sulfur mustard in tyrods buffer .After 8 weeks rats were killed. The samples were fixed in formaldehyde solution [%10], stained with H and E and studied with light microscope
Results: Increased distance between seminiferous tubules. Accumulation of necrotic materials of the cells in the lumen of seminiferous, oligospermia, displacement of somniferous tubules and changing the situation of sertoli nuclei from the abdominal positioning to basal in both groups of sulfur mustard that compared with normal and tyrods groups
Conclusion: Presence of necrotic form of spermatocytes and necrotic cells with picnotic nuclei in both sulfur mustard groups but more in 10 mg/kg HD
RESUMEN
Background: Renal colic is a common cause of acute severe pain. Opioids and non-opioids analgesics and NSAIDs and phosphodiesterase enzyme [PDE] inhibitors are four medical cathegories that recommended for treatment, but the relative efficacy of these drugs is uncertain
Materials and Methods: To examine the benefits and disadvantages of pethidine, piralgin, diclofenac and aminophyllin for the management of pain in acute renal colic, as a randomised clinical trial study, patients with four suspected renal colic [n=200] were randomised to receive these 4-drugs at emergency ward of -hospitals. Pain relief and side effects was assessed at one hour after the analgesics. Datas has been analised by statistical soft ware of SPSS-ver.11
Results: pain reliefed in the pethidine group after 30 minute and one hour was %60 [30 patients] and %94 [47 patients], for piralgin group was %54 [27 patients] and %92 [46 patients], diclofenac group was %28 [14 patients] and %68 [34 patients] and for aminophylline was %24 [12 patients] and %62 [31 patients]. [P< 0/05] The side-effects of 4-groups was included: pethidine: nausea [11 Patients], vomiting [7 Patients], respiratory depression [3 Patients] and headache [2 Patients]; piralgin [3 Patients]; aminophylline: orthostatic hypothension [7 Patients], vertigue [9 Patients], headache [12 patients]; diclofenac had no side-effect
Conclusion: Tramadol response was as same as pethidine but less side-effects. diclofenac is a good choice for mild pain; but aminophyllin had a bad response with very much side-effects
RESUMEN
Background: Human sperm heads which present disturbances of choranatin condensation are stained by acidic aniline blue. To determine whether the proportion of unstained heads, i.e with well condensed chromatin, can be considered as an index of sperm quality
Materials and Methods: stady was undertaken in 20 infertile patients with spinal cord injure and 20 intetile patients with non- spinal cord injure. In addition to the usual sperm characteristics, the percentages of unstained heads and of morphologically normal and abnormal forms were concomitantly evaluated
Results: The results obtained in this research show a significant relationship between the mean of sperm volume, concentration, validity and motility
Conclusion: In scipationts and the results taken by previous researchers. In addition the mean of sperm morphology and sperm condensation between the two groups was not significant so we can say that s.ci has no signiticant effected on condensation of chromatin of sperm