evaluation of ovarian cancer symptoms and risk factors in patients of hazrat-e-rasool and Shahid Akbarabadi hospitals

Ovarian cancer is the most fatal gynecologic malignancy. New methods for detecting this cancer, has no significant effect on patients survival. One of the most important reasons is this fact that patients detect lately. Therefore identification of this cancer symptoms and signs can be effective in its early diagnose and reduction of mortality. This investigation was a cross sectional study that was performed on 89 patients with ovarian cancer and 89 people as control group. The collection of data was done to according of questionnaire of ovarian cancer risk factors and patients complains. Then data was compared between two groups and analyzed by SPSS version 16 software. The incidence of ovarian cancer was 0.67%. 20.8% of patient group had infertility or nulliparity history. Incidence of cancer in these patients significantly was more than other in this group [p=0.03]. Using oral contraceptive has a prophylactic effect [p<0.01]. The correlation between breast cancer history and incidence of ovarian cancer was significant [p<0. 01]. Abdominal pain, sense of abdomen or pelvic mass, infertility, gastrointestinal problems and abnormal uterine bleeding must be considered as other important symptoms as well. According to results of investigation, incidence of mentioned symptoms must be noticed for rule out of ovarian cancer, specifically in patients who have ovarian cancer risk factors

[Evaluation of correlation between maternal serum level of beta-human chorionic gonadotropin during 16-20 weeks of pregnancy and preeclampsia incidence]

Most current hypotheses Background: regarding the pathophysiologic mechanisms of preeclampsia point to early placental abnormalities. Therefore, we attempted to determine whether maternal human chorionic gonadotropin [hCG] levels in second trimester predict preeclampsia. In this prospective study, 508 pregnant women who referred to Shahid Akbar Abadi prenatal clinic for prenatal care during 2007-2009 were enrolled. Maternal serum hCG was measured of all these women during 16-20 wks of gestational age. All these women were followed and evaluated for preeclampsia. In 47 women [9.3%], preeclampsia was detected. The mean of log serum hCG levels during second trimester of pregnancy were found to be significantly higher in severe preeclampsia, compared with controls [p<0.05]. Furthermore, increase of maternal age enhances risk of preeclampsia. Our finding indicates that a serum level of maternal hCG during weeks 16-20 pregnancy, could be a value for predicting of preeclampsia

[Evaluation of correlation between maternal serum level of beta-human chorionic gonadotropin during 16-20 weeks of pregnancy and preeclampsia incidence]

Background: most current hypotheses Background: regarding the pathophysiologic mechanisms of preeclampsia point to early placental abnormalities. Therefore, we attempted to determine whether maternal human chorionic gonadotropin [hCG] levels in second trimester predict preeclampsia

Materials and Methods: in this prospective study, 508 pregnant women who referred to Shahid Akbar Abadi prenatal clinic for prenatal care during 2007-2009 were enrolled. Maternal serum hCG was measured of all these women during 16-20 wks of gestational age. All these women were followed and evaluated for preeclampsia

Results: in 47 women [9.3%], preeclampsia was detected. The mean of log serum hCG levels during second trimester of pregnancy were found to be significantly higher in severe preeclampsia, compared with controls [p<0.05]. Furthermore, increase of maternal age enhances risk of preeclampsia

Conclusions: our finding indicates that a serum level of maternal hCG during weeks 16-20 pregnancy, could be a value for predicting of preeclampsia