RESUMEN
A total of 17 patients [14 males and 3 females], with age range from 18 to 40 years with a mean of 29 years, were subjected to autologs bone marrow transplantation in Maadi Armed Forces Hospital. The cause of transplantation was due to AML, CR1, CR2 in 3 patients, refractory non-Hodgkin's lymphoma in 7 patients, refractory Hodgkin's lymphoma in 5 patients and 2 patients were suffering from ALL. Pretransplantation routine blood investigation and chemotherapy regimen for conditioning were performed according to the Royal Free Hospital [U.K.] protocol, [personal communication]. The final outcome of these patients was as follows: 12 patients had complete remission [70.6%], 1 patient had initial disease relapse [5.9%] and 4 [23.5%] deaths. Major complications and causes of death were septicemia in 2 patients, hepatic failure in 1 patient and renal failure in another one. Veno- occlusive disease was a complication in one patient. No failure of engraftment was detected. In conclusion, preliminary study on bone marrow transplantation outcome demonstrated a high success rate. However, better selection of cases and more experience will improve the outcome to that reported in specialized centers abroad