Diagnostic value of nucleolar organizer regions [NORs] in endometrial hyperplasia and adenocarcinoma

Thirty six endometrial curette samples [10 cystic hyperplasia, 16 adenomatous hyperplasia without atypia, 3 glandular hyperplasia with atypia and 7 cases of endometrial adenocarcinoma] were studied for counting the NORs. There is a significant rise in NORs count in glandular hyperplasia with atypia and adenocarcinoma when compared with cystic hyperplasia or adenomatous type without atypia. No significant changes in the NORs count between the adenocarcinoma and the glandular hyperplasia with atypia were shown