Hallermann-streiff syndrome a case report from Egypt

Hallermann-Streiff syndrome [HSS] is a rare genetic disorder that is primarily characterized by distinctive malformations of the skull and facial [craniofacial] region; sparse hair [hypotrichosis]; eye abnormalities; dental defects; degenerative skin changes [atrophy], particularly in the scalp and nasal regions; and proportionate short stature. Here we describe a case with HSS

Western blot in comparison with ELISA for detecting antibodies against foot and mouth disease virus

Western blot technique is described for visual detection of foot and mouth disease virus [FMDV] antibodies in sera of infected, vaccinated and field cattle using FMDV fragments separated by SDS-PAGE and blotting onto nitrocellulose membrane. The interaction between FMDV antibodies and blotting virus fragments revealed dark blue bands, which is considered a positive result by Western blot. All sera of infected, vaccinated bulls and 10 out of 38 field animals had antibody titers ranged from 1.7 to 3.1 by ELISA. All ELISA positive sera demonstrated dark blue bands against the different FMDV fragment by Western blot. The use of Western blot as a rapid specific and sensitive technique for detecting FMDV antibodies was discussed

effect of maternally derived antibodies on the response of calves to vaccination against Kabete O rinderpest vaccine

A study was undertaken to find out the age at which calves borne to repeatedly vaccinated dame could be vaccinated against rinderpest [RP]. Eight vaccination regimes on eight groups of colostrums fed calves were implemented using a local live attenuated cell culture RP vaccine. The animals of regimes 1,2,3,4,5,6,7 and 8 were primary vaccinated at the age of 1,2,3,4,5,6,7 and 8 month respectively and boosted at the age of 6,7and 9 month in regimes 1 to 5 and at 9 months in regimes 6,7 and 8. Maternally derived antibody [MDA] and vaccine-induced antibody against rinderpest antigen were assessed using competitive ELISA and the detected antibodies are expressed as percent inhibition [PI] values. The sera that had P1 below 42 tested negative. Two days following feeding colostrum calves revealed highest PI [94.5-92.2]. MDA gradually declined to undetectable levels by the age of 4 to 6 months. Early vaccination regimes before the age of 6 months were ineffective ligier antibody levels were detected at the age of 7 months in the animals of regimes I,2,3,4,5 and one month after primary vaccination in regimes 6,7 and 8. Based on the above finding, it is recommended that the colostrum fed calves could be vaccinated against Rinderpest when they are at 6 to 7 months of age