Association of insulin-like growth factor-1 [IGF-1], dietary intake and cognitive functions in normal school age children

Insulin-like growth factor I [IGF-I] is a hormone that mediates the effects of growth hormone and plays a critical role in somatic growth regulation and organ development. It is hypothesized that it also plays a key role in human brain development. The dietary determinants of circulating levels of components of the IGF system are of interest, as these may mediate some of the effects of diet on later health. However, few studies have examined the relationship between diet and IGF-1 levels in children, as well as the relationship between IGF-1 and mental development. To investigate the role of diet on levels of IGF-I and their relationships with measures of IQ in a group of healthy children. The study included 222 apparently healthy children [113 boys and 109 girls], their height for age and weight for age were between 10[th]-90[th] percentiles according to World Health Organization [WHO] growth standards, their age ranged 8-11 years and all were prepubescent. They were chosen randomly from primary schools located in urban Giza Governorate. Nutritional status was assessed by 24-hours dietary intake history and anthropometric measurements [weight, height]. Plasma IGF-1 was evaluated by radioimmu-noassay technique, growth hormone [GH] was determined by immuno-enzymatic assay. Intelligence quotient [IQ] was measured with the Arabic version of the revised-Wechsler Intelligence Scale for Children. Familial background was investigated through structured questionnaire. IGF-1 levels [mean +/- SD] were 142.6 +/- 43.3 ng/mL for girls and 139.4 +/- 39.6ng/mL for boys. GH level was within normal range. IQ scores [mean +/- SD] were 101.03 +/- 17.4 and 103.11 +/- 19.8 for boys and girls, respectively. IGF-1 levels were associated positively with IQ [r=0.81, p

Correlation between widal test and some liver function tests

34 patients [aged 15-40 years] with positive stool cultures for Salmonella typhi were included in this study. Their sera were tested by slide agglutination which proved to be positive for Salmonella typhi. Widal test was further done to determine the antibody titre. Some liver function tests were simultaneously done, aiming at finding any correlation between the antibody titre and liver functions. The results were discussed

Athermic scleral buckling with postoperative photocoagulation for treatment of primary rhegmatogenous retinal detachment

This work aimed at the evaluation of photocoagulation as a tool in treating retinal detachment by creating a chorioretinal reaction around the retinal tear[s] after their operative support by an athermic buckle and subretinal fluid evacuation. The limitations, results and complications of the technique are discussed

Comparative study of CRP, fibrinogen and thrombocytes in clean trauma, acute tonsillitis and rheumatoid arthritis in adults and children

The study was made on 31 candidates comprising 10 controls, 5 post operative cases, 10 cases with acute tonsillitis and 6 cases with rheumatoid arthritis. Among participants were 12 children in the various groups. For all candidates blood fibrinogen, C.R.P. and platelet count were assayed [in the post operative cases at 3-two days intervals]. The results revealed certain differences in magnitude of response between the three parameters in the three diseases tested. An attempt was made at the explanation of such differences in the light of the known attributes of the various parameters in relation to the nature of the disease as well as the vector balance between excessive generation versus consumption. Disease preferentiality rather than specificity seems to be the key word in the acute phase response