Circulating nitric oxide [NO] in acute attacks of bronchial asthma

Thirty patients with bronchial asthma were included in this study. The airway reversibility in pulmonary function tests including forced vital capacity [FVC], forced expiratory volume in the first second [FEV1] and peak expiratory flow rate [PEFR] was more than 15% after the use of salbutamol inhaler. Venous blood levels of total nitrous oxide metabolites as serum nitrite and nitrate during and in-between acute asthmatic attacks were measured. ABGs were measured during and in-between asthmatic attacks. From the results obtained, it was concluded that the circulating nitric oxide level is suppressed in acute attacks of bronchial asthma, this is promptly reversible with the relief of the acute attacks

Practice of tonsillectomy among Egyptian children

This study was carried out on 1000 tonsillectomized children from E N T and pediatric departements- Al-Azhar University Hospitals. Their age ranged from 3to 15 years. They were 570 males and 430 females. The parents of children were interviewed through a previously prepared questionnaire sheets including personal data, social status, level of education, indications for tonsillectomy, frequency of the attacks of tonsillitis and the treatment given. All these children were clinically evaluated

Correlative study of oral lactose hydrogen breath test, lactase activity and intestinal morphology in Giardia lamblia infected children

Oral Lactose Hydrogen Breath Test [OLHBT], biochemical assay of lactase activity [LA] and histomorphologie examination of jejunal biopsies were done in 30 children [6-12 years old and both sexes] with abdominal pain and stools analysis showing trophozoites and cysts of Giardia Lamblia [GL] compared to 30 normal control of the same age group and sexes. The results showed that there was significantly increased incidence of hypolactasia in cases with giardiasis compared to control group [33.3% 10.0% respectively]. Also, the study showed that LA was significantly decreased in infected group compared to control group. Concerning histomorphologic changes in the form of shortening, atrophy and chronic cellular infiltration were present in 30% of cases. There was significantly increased incidence of abnormal histomorphologic lesions of the small intestinal mucosa in Giardiasis compared to control group. Lastly, in present work, upon doing matrix correlation the results showed that medium negative correlation was observed between the grade of histopathologic features of jejunal biopsies and the LA [micro t molgram/min] while medium positive correlation was noted between the grade of histopathologic features of Jejunal biopsies and maximum rise in H2 breath concentration [p.p.m] detected by OLHBT