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New Egyptian Journal of Medicine [The]. 1994; 10 (5): 2224-7
en Inglés | IMEMR | ID: emr-34360

RESUMEN

Pirimor, a carbamate pesticides, was evaluated for its genotoxic effects on male germ cells and sterility in Drosophila melangogaster, by the well-known sex linked recessive lethal test. 2 concentrations LC50 and LC5 [0.47% and 0.33%] were used following one route of administration adult feeding. After single exposure, the results showed that at high concentration Pirimor induced significant increase of mutation frequencies in the first 2 broods of spermatogenesis which decreased gradually in the other germ-cell stages. On the contrary, value of lethals at LC5 [0.33%] were insignificant in all broods of spermatogenesis. Steriles induced by Pirimor were higher in the first 2 broods than the others stages at both concentrations. Lethalities as well as sterility exhibited a concentration and stage-dependent effect


Asunto(s)
Humanos , Masculino , Células Germinativas/efectos de los fármacos
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