Synthesis and antischistosomal activity of some new thiazolidinones and 1,3,4-thiadiazoline

In this study, new series of thiazolidinones 3a-e was synthesized by the cyclocondensation of the Schiff bases 2a-e with mercaptoacetic acid. The thiadiazole 5 was obtained by refluxing 4 with carbondisulfide. The antischistosomal activity was determined for the new representative compounds