Effect of aqueous extract of Ocimum sanctum Linn. [Labiateae] on gastrointestinal tract

The effect of O. sanctum L. on gastrointestinal [GI] motility by BaSO4 revealed that O. sanctum L. aqueous extract significantly increased the peristaltic movement of GI tract compared to control. But the in vitro result on isolated guinea pig ileum differs from the in vivo gastrointestinal motility result. The in vitro result of hot water extract showed a dose dependent increase in relaxation on isolated guinea pig ileum similar to previous findings and it showed no interaction with acetylcholine