RESUMEN
Objective: The aim of this study was to investigate the association between platelet-to-lymphocyte ratio [PLR] and atrial fibrillation [AF] after coronary artery bypass graft [CABG] surgery
Subjects and Methods: A total of 125 patients were retrospectively analyzed. AF was diagnosed using standard clinical criteria, and PLR was calculated as the ratio of the platelets to lymphocytes, obtained from the blood samples that were taken in the fasting state before CABG surgery. The association of different variables with postoperative AF and PLR was calculated using univariate and multivariate analysis. The receiver operating characteristics curve was used to determine the sensitivity and specificity of PLR and the optimal cutoff value for predicting post-CABG AF
Results: Of the 125 patients, 50 with AF [mean age: 67.0 +/- 9.5 years, 38 males and 12 females] and 75 patients without AF [mean age: 61.1 +/- 9.1 years, 58 males and 17 females] were identified, and the difference in the mean age was statistically significant [p = 0.01]. PLR was also significantly higher in those with AF [152.8 +/- 82.2] than those without AF [118.2 +/- 32.9] [p = 0.012]. Univariate analysis showed that age and PLR were associated with AF after CABG surgery [p < 0.001 and p = 0.005, respectively]. Using a multivariate logistic regression model with the backward elimination method, age and PLR remained as independent predictors of AF after CABG surgery [p < 0.001 and p = 0.005, respectively]. PLR levels >119.3 predicted postoperative AF with 64% sensitivity and 56% specificity [AUC: 0.634, p = 0.012]
Conclusion: In this study, age and PLR level were independent predictors of AF after CABG surgery. Patients with an elevated preoperative PLR were at higher risk of AF after CABG surgery
RESUMEN
Objective: The aim of this study was to highlight the use of combined intravenous lipid emulsion [ILE] and plasma exchange [PE] therapies in multidrug toxicity
Clinical Presentation and Intervention: A 45-year-old woman who attempted suicide by ingesting large quantities of amisulpride [28 g], diazepam [250 mg], valsartan [2,240 mg], aripiprazole [45 mg] and paliperidone [21 mg] was taken to the hospital of Adnan Menderes University School of Medicine. Upon arrival, she exhibited signs of cardiotoxicity and severe depression of the central nervous and respiratory systems. She was treated successfully with ILE for 4 h and PE therapy for 36 h, consecutively. She was discharged on the fourth day of hospitalization having fully recovered
Conclusion: The patient was successfully treated with the combination of ILE and PE. Effect and metabolism. Multiple treatment modalities including antidotes of medication, charcoal, lipid emulsion therapy, specific anticore to the drug and plasma exchange [PE] have been used based on the mechanism of drug intoxication. Here, we present a case of multiple medication toxicity and successful patient management
RESUMEN
The aim of this study was to evaluate the association of the levels of red blood cell distribution width [RDW] with the severity of atherosclerosis and to determine whether or not the RDW level on admission is an independent predictor of all-cause mortality in patients with non-ST elevation myocardial infarction [NSTEMI]. Materials and A total of 335 consecutive patients with NSTEMI were enrolled in this study. The patients were divided into high [n = 105] and low [n = 230] SYNTAX groups. The high SYNTAX group was defined as patients with a value in the third tertile [SYNTAX score, SXscore >/=12], while the low SYNTAX group was defined as those with a value in the lower 2 tertiles [SXscore <12]. The high RDW group [n = 152] was defined as patients with RDW >14.25% and the low RDW group [n = 183] as those with RDW ?14.25%. All-cause mortality was followed up to 38 months. The mean follow-up period was 18 +/- 11 months. The RDW levels of patients were significantly higher in the high SYNTAX group than in the low SYNTAX group [15.2 +/- 1.8 vs. 14.2 +/- 1.2, p < 0.001]. Pearson's coefficients were used to determine the degree of association between RDW levels and SXscore and also between RDW levels and high-sensitivity C-reactive protein. There was a significant correlation between RDW levels and SXscore [r = 0.460, p < 0.001]. Also, there was a significant correlation between RDW levels and high-sensitivity C-reactive protein [r = 0.180, p = 0.001]. All-cause mortality rate was not significantly different between the high and low RDW groups [log-rank, p = 0.621]. RDW levels were independently associated with high SXscore but were not associated with long-term mortality in NSTEMI patients