precise mechanism of action of fish oil [omega-3-fatty acid] in amelioration postmenopausal osteoporosis in female rats

This work studied the mechanism of the action of fish oil rich in eicosapentaenoic acid [EPA] and docasahexaenoic acid [DHA] [omega-3 fatty acid] on postmenopausal symptoms and bone resorption in intact and ovariectomized [ovx] female rats. The effects of dietary supplementation of fish oil [omega-3 fatty acid] for eight weeks on hypothalamic-pituitary-gonadal axis, bone formation markers, bone resorption markers and bone mineral metabolism were tested. It was concluded that the resulted data could be the protective mechanisms of fish oil against postmenopausal osteoporosis. These mechanisms based on promote positive calcium balance, increase osteoblastic bone formation and decreased bone resorption

Evaluation of a synthetic peptide-based assay and a rapid blot recombinant test for detection of antibodies to HIV-1 and HIV-2

The objective of this study was to evaluate two new serologic assays for detecting HIV-form 1 and HIV-2 positive and negative sera. A total of 154 human sera from Egypt and African countries was tested using a synthetic peptide-based passive hemagglutination assay [PHA] and a rapid dot-blot recombinant test [Test-Pack], both of which are marketed as HIV-1/HIV-2 combination assays. The results indicated that the PHA identified all HIV-1 and HIV-2 positive sera, although some reacted only weakly. It produced one false positive reaction. The Test-Pack correctly detected all positive sera and three false negatives. All tests ran concurrently. Both identified HIV-2 positive antibodies and HIV-1 positive antibodies sera

Evaluation of a synthetic peptide-based assay and a rapid dot-blot recombinant test for detection of antibodies to HIV-1 and HIV-2

Our objective was to evaluate two new serologic assays for detecting HIV-1 and HIV-2 positive and negative sera. A total of 154 human sera from African countries were tested using a synthetic peptide-based passive hemagglutination assay [PHA] and a rapid dot-blot recombinant test [Test-Pack], both of which are marketed as HIV-l/HIV-2 combination assays. Results indicated that the PHA identified all HIV-1 and HIV-2 positive sera, although some were only weakly reactive. It produced one false positive reaction. The Test-Pack correctly detected all positive and negative sera, although several negative sera produced extremely weak reactions. Both tests detected two HIV-2 positive sera which were non-reactive by HIV-1 screening assays