RESUMEN
Hypercholesterolemia is a major risk factor for cardiovascular diseases. Portulaca oleracea is a vegetable, known in traditional medicine and has many medicinal properties. In the present study the effects of alcoholic extract of Portulaca oleracea on blood fat profiles are evaluated. In this experimental study, 60 Wistar rats in the weight range of 170 +/- 5 g in 6 groups [n=10] were selected as follows: Control group receiving normal diet, Sham group receiving high fat diet, experimental groups receiving the Portulaca oleracea extract with maximum dose [800 mg/kg], moderate dose [400 mg/kg] and minimum dose [200 mg/kg] as intraperitoneally and injection of 10 mg/kg atorvastatin and treated with high fat diet for 21 days. After the end of this period, blood sampling and measuring obtained samples, data was analyzed using SPSS-11.5 software. Based on the results obtained from all groups receiving the extract of Portulaca oleracea herb, it was found that the level of cholesterol concentration in these groups and the level of cholesterol and triglyceride concentrations in the group receiving atorvastatin significantly decreased [p
RESUMEN
Training and continuous dynamic communication between patients and health professionals in chronic diseases like diabetes, is important. The aim of this study is to evaluate the effects of diabetes self-care group education and nurse- telephone follow-up on glycemic control and compliance with treatment orders in patients with type 2 diabetes attending to diabetes clinic in Khomein. In this clinical trial, 62 patients with type 2 diabetes who attending to the diabetes clinic selected and were randomly assigned to experiment and control groups. Self-care group education was applied for case group [n = 31] and they were followed up using telephone calls for 12 weeks by a nurse. The control group [n = 31] received the conventional management. Demographic characteristics, compliance with treatment recommendations [diet, drug use, exercise] and blood glucose control indices were recorded before and after interventions. Data were analyzed by SPSS software version 16 using independent t-test, paired t-test, Chi-square test, non-parametric tests, mixed model [ANOVA + repeated measure] and ANCOVA. The mean age of intervention and control groups was 50.9 +/- 7.3 and 55.1 +/- 10.1 years, respectively. Blood glucose indices [FBS, 2 hpp BS, Hb A1C] were improved in both case and control group after intervention but it was only statistically significant in case group [P > 0.0001]. During study, percentage of patients with very good compliance in control group decrease from 12.5% to zero [0%], whereas in experiment group these amounts increase from 6.5% to 90.3% [P > 0.0001]. According to the results of the current study self-care group education and 12 weeks follow-up by a nurse using telephone causes significant improvement in metabolic parameters and adherence to treatment recommendations in diabetic patients